Targeting the alpha 7 nicotinic acetylcholine receptor to reduce amy loid accumulation in alzheimer's disease pyramidal neurons : Drug Targets in Alzheimer's Disease
- Author
- D'ANDREA, Michael R1 ; NAGELE, Robert G2
[1] Johnson & Johnson Pharmaceutical Research & Development, Drug Discovery, Spring House, Pennsylvania, 19477, United States
[2] University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, Stratford, New Jersey 08084, United States - Source
Current pharmaceutical design. 2006, Vol 12, Num 6, pp 677-684, 8 p ; ref : 82 ref
- ISSN
- 1381-6128
- Scientific domain
- Pharmacology drugs
- Publisher
- Bentham Science, Hilversum
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Abeta42 Alzheimer's disease Purkinje cell amyloid plaque formation astrocyte blood-brain barrier nicotinic acetylcholine receptor pyramidal cell
- Keyword (fr)
- Accumulation biologique Amyloïde Astrocyte Barrière hématoencéphalique Ciblage Cible Démence Alzheimer In vitro Neurone pyramidal Plaque sénile Récepteur cholinergique Récepteur nicotinique Encéphale pathologie Maladie dégénérative Névroglie Pharmacocinétique Système nerveux central pathologie Système nerveux central Système nerveux pathologie
- Keyword (en)
- Biological accumulation Amyloid Astrocyte Blood brain barrier Targeting Target Alzheimer disease In vitro Pyramidal neuron Senile plate Cholinergic receptor Nicotinic receptor Cerebral disorder Degenerative disease Neuroglia Pharmacokinetics Central nervous system disease Central nervous system Nervous system diseases
- Keyword (es)
- Acumulación biológica Amiloide Astrocito Barrera hematoencefálica Blancado Blanco Demencia Alzheimer In vitro Neurona piramidal Placa senil Receptor colinérgico Receptor nicotínico Encéfalo patología Enfermedad degenerativa Neuroglia Farmacocinética Sistema nervosio central patología Sistema nervioso central Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17559184
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/138161206775474224 
https://dx.doi.org/10.2174/138161206775474224
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