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Semi-synthetic preparation of the rare, cytotoxic, deep-sea sourced sponge metabolites discorhabdins P and U

Author
GRKOVIC, Tanja1 ; KAUR, Balwinder1 ; WEBB, Victoria L2 ; COPP, Brent R1
[1] Department of Chemistry, The University of Auckland, Private Bag 92019, Auckland, New Zealand
[2] National Institute of Water and Atmospheric Research Lid, Private Bag 14901, Wellington, New Zealand
Source

Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 7, pp 1944-1946, 3 p ; ref : 22 ref

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Cytotoxic Discorhabdin Latrunculia Marine alkaloid
Keyword (fr)
Activité biologique Alcaloïde Anticancéreux Composé naturel Cytotoxicité Enzyme Eponge Hémisynthèse Milieu marin Métabolite Méthylation Origine animale Pharmacognosie Porifera Quinone imine Synthèse chimique Discorhabdine U dérivé Discorhabdine Latrunculia Pyrroloiminoquinone Spiro[cyclohexane-1,10'-pyrrolo[4,3,2-de]-1,7-phénanthroline] dérivé Invertebrata
Keyword (en)
Biological activity Alkaloid Antineoplastic agent Natural compound Cytotoxicity Enzyme Sponge Hemisynthesis Marine environment Metabolite Methylation Animal origin Pharmacognosy Porifera Quinone imine Chemical synthesis Invertebrata
Keyword (es)
Actividad biológica Alcaloide Anticanceroso Compuesto natural Citotoxicidad Enzima Esponja Hemisíntesis Medio marino Metabolito Metilación Origen animal Farmacognosia Porifera Quinona imina Síntesis química Invertebrata
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06C Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A04 Pharmacognosy. Homeopathy. Health food

Discipline
General pharmacology Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17561112

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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