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Insertional mutagenesis at positions 520 and 584 of adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors with eliminated heparin-binding ability and introduced novel tropism

Author
XIANGQUN SHI1 ; GUANGGUANG FANG2 ; WENFANG SHI3 4
[1] Department of Neurology, Lanzhou Military District General Hospital, Lanzhou 730050, China
[2] Department of Obstetrics and Gynecology, 2nd People's Hospital in Shenzhen, Shenzhen 518029, China
[3] Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
[4] Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Source

Human gene therapy. 2006, Vol 17, Num 3, pp 353-361, 9 p ; ref : 29 ref

CODEN
HGTHE3
ISSN
1043-0342
Scientific domain
Genetics
Publisher
Liebert, Larchmont, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Anticoagulant Capside Dependovirus Gène Héparine Mutagenèse Thérapie génique Tropisme Vecteur Parvoviridae Parvovirinae Virus
Keyword (en)
Anticoagulant Capsid Dependovirus Gene Heparin Mutagenesis Gene therapy Tropism Vector Parvoviridae Parvovirinae Virus
Keyword (es)
Anticoagulante Cápside Dependovirus Gen Heparina Mutagénesis Terapia génica Tropismo Vector Parvoviridae Parvovirinae Virus
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C07 Mutagenesis. Repair

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31D Industrial applications and implications. Economical aspects / 002A31D01 Health. Pharmaceutical industry / 002A31D01D Gene therapy

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B27 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy / 002B27D Transfusions. Complications. Transfusion reactions. Cell and gene therapy / 002B27D03 Applied cell therapy and gene therapy

Discipline
Anaesthesia. Reanimation. Transfusion. Cell therapy and gene therapy Biotechnology Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17650659

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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