Inhibiting matrix metalloproteinases with prinomastat produces abnormalities in fetal growth and development in rats
- Author
- YOUNIS, Husam S1 ; JESSEN, Bart A1 ; WU, Ellen Y2 ; STEVENS, Gregory J1
[1] Worldwide Safety Sciences, Pfizer Global Research and Development, La Jolla Laboratories, San Diego, California, United States
[2] Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, La Jolla Laboratories, San Diego, California, United States - Source
Birth defects research. Part B. Developmental and reproductive toxicology. 2006, Vol 77, Num 2, pp 95-103, 9 p ; ref : 41 ref
- ISSN
- 1542-9733
- Scientific domain
- Medical oncology; Embryology, development; Genetics; Toxicology
- Publisher
- Wiley-Liss, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- embryo/fetal toxicity matrix metalloproteinase inhibitors matrix metalloproteinases prinomastat rat embryo cultures rats
- Keyword (fr)
- Animal Croissance Culture embryon Développement foetal Embryon Foetus In vitro Inhibiteur enzyme Metalloendopeptidases Mécanisme action Prinomastat Rat Toxicité Matrix metalloproteinase Matrix metalloproteinases Enzyme Hydrolases Mammalia Peptidases Rodentia Vertebrata
- Keyword (en)
- Animal Growth Embryo culture Fetal development Embryo Fetus In vitro Enzyme inhibitor Metalloendopeptidases Mechanism of action Prinomastat Rat Toxicity Enzyme Hydrolases Mammalia Peptidases Rodentia Vertebrata
- Keyword (es)
- Animal Crecimiento Cultivo embrionario Desarrollo fetal Embrión Feto In vitro Inhibidor enzima Metalloendopeptidases Mecanismo acción Prinomastat Rata Toxicidad Enzima Hydrolases Mammalia Peptidases Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U10 Miscellaneous (drug allergy, mutagens, teratogens...)
- Discipline
- Drugs toxicity and drug intoxications Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17718199
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/bdrb.20073 
https://dx.doi.org/10.1002/bdrb.20073
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