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Carboxylesterases - detoxifying enzymes and targets for drug therapy

Author
POTTER, Philip M1 ; WADKINS, Randy M2
[1] Department of Molecular Pharmacology, St. Jude Children's Research Hospital, Memphis, TN 38105, United States
[2] Department of Chemistry and Biochemistry, University of Mississippi, University, MS 38677, United States
Source

Current medicinal chemistry. 2006, Vol 13, Num 9, pp 1045-1054, 10 p ; ref : 59 ref

ISSN
0929-8673
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Bentham Science, Schiphol
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Carboxylesterase drug metabolism enzyme structure inhibitor
Keyword (fr)
Carboxylesterase Détoxication Inhibiteur enzyme Modèle moléculaire Modélisation Médicament Métabolisme Prédiction Relation structure activité Site actif Substance toxicomanogène Carboxylic ester hydrolases Enzyme Esterases Hydrolases
Keyword (en)
Carboxylesterase Detoxification Enzyme inhibitor Molecular model Modeling Drug Metabolism Prediction Structure activity relation Active site Drug of abuse Carboxylic ester hydrolases Enzyme Esterases Hydrolases
Keyword (es)
Carboxylesterase Detoxicación Inhibidor enzima Modelo molecular Modelización Medicamento Metabolismo Predicción Relación estructura actividad Lugar activo Sustancia toxicomanógena Carboxylic ester hydrolases Enzima Esterases Hydrolases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03D Drug addictions

Discipline
General pharmacology Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17733775

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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