Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats
- Author
- VAN VLIET, Erwin A1 2 ; VAN SCHAIK, Rosalinde2 ; EDELBROEK, Peter M1 ; REDEKER, Sandra3 ; ARONICA, Eleonora3 ; WADMAN, Wytse J2 ; MARCHI, Nicola4 ; VEZZANI, Annamaria4 ; GORTER, Jan A1 2
[1] Epilepsy Institute of The Netherlands (SEIN), Heenistede, Netherlands
[2] Swammerdam Institute for Life Sciences, Center for Neuroscience, Netherlands
[3] Department of (Neuro) Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[4] Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri,, Milano, Italy - Source
Epilepsia (Copenhagen). 2006, Vol 47, Num 4, pp 672-680, 9 p ; ref : 46 ref
- Publisher
- Blackwell, Malden, MA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Pharmacoresistance-Antiepileptic drug-Tariquidar-Blood- brain barrier-Temporal lobe epilepsy
- Keyword (fr)
- Animal Anticancéreux Anticonvulsivant Barrière hématoencéphalique Chronique Epilepsie temporale Epilepsie Glycoprotéine Phénytoïne Rat Système nerveux pathologie Tariquidar Traitement Encéphale pathologie Epilepsie partielle complexe Mammalia Rodentia Système nerveux central pathologie Système nerveux central Vertebrata
- Keyword (en)
- Animal Antineoplastic agent Anticonvulsant Blood brain barrier Chronic Temporal lobe epilepsy Epilepsy Glycoprotein Phenytoin Rat Nervous system diseases Tariquidar Treatment Cerebral disorder Complex partial epilepsy Mammalia Rodentia Central nervous system disease Central nervous system Vertebrata
- Keyword (es)
- Animal Anticanceroso Anticonvulsivante Barrera hematoencefálica Crónico Epilepsia temporal Epilepsia Glicoproteína Fenitoína Rata Sistema nervioso patología Tariquidar Tratamiento Encéfalo patología Epilepsia parcial compleja Mammalia Rodentia Sistema nervosio central patología Sistema nervioso central Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25D Central nervous system / 002A25D04 Central neurotransmission. Neuromudulation. Pathways and receptors
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B06 Anticonvulsants. Antiepileptics. Antiparkinson agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A03 Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
- Discipline
- Neurology Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology Vertebrates : nervous system and sense organs
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17736766
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1528-1167.2006.00496.x 
https://dx.doi.org/10.1111/j.1528-1167.2006.00496.x
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