Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype
- Author
- ZHENGWEN JIANG1 ; DRAGIN, Nadine1 ; SALDANA, Shannon N6 ; SORTER, Michael7 ; VINKS, Alexander A6 ; NASSR, Nassr8 ; VON RICHTER, Oliver9 ; LI JIN1 ; NEBERT, Daniel W1 ; JORGE-NEBERT, Lucia F1 ; MARTIN, Martha V2 ; GUENGERICH, F. Peter2 ; AKLILLU, Eleni3 ; INGELMAN-SUNDBERG, Magnus4 ; HAMMONS, George J5 ; LYN-COOK, Beverly D5 ; KADLUBAR, Fred F5
[1] Department of Environmental Health and Center for Environmental Genetics (CEG), University of Cincinnati Medical Center, Cincinnati, Ohio, United States
[2] Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States
[3] Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital-Huddinge, Karolinska Institutet, Stockholm, Sweden
[4] Division of Molecular Toxicology, IMM, Karolinska Institutet, Stockholm, Sweden
[5] Division of Pharmacogenomics and Molecular Epidemiology, National Center for Toxicological Research, Jefferson, Arkansas, United States
[6] Pediatric Pharmacology Research Unit, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
[7] Division of Child and Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
[8] Department of Clinical Pharmacology, ALTANA Pharma AG, Konstanz, Germany
[9] Division of Drug Metabolism and Pharmacokinetics, ALTANA Pharma AG, Konstanz, Germany - Source
Pharmacogenetics and genomics (Print). 2006, Vol 16, Num 5, pp 359-367, 9 p ; ref : 48 ref
- ISSN
- 1744-6872
- Scientific domain
- Genetics; Pharmacology drugs
- Publisher
- Lippincott Williams and Wilkins, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- 4-aminobiphenyl N-hydroxylase 7-ethoxyresorufin O-deethylase CYP1A2 activity genotype-phenotype association study human CYP1A2 gene urinary caffeine metabolic ratio
- Keyword (fr)
- Analeptique respiratoire Association Caféine Gène Génotype Homme Hydroxylase Pharmacogénétique Phénotype Psychotrope Stimulant SNC Urine Cytochrome CYP1A2 Enzyme Oxidoreductases
- Keyword (en)
- Respiratory analeptic Association Caffeine Gene Genotype Human Hydroxylase Pharmacogenetics Phenotype Psychotropic CNS stimulant Urine Enzyme Oxidoreductases
- Keyword (es)
- Analéptico respiratorio Asociación Cafeína Gen Genotipo Hombre Hydroxylase Farmacogenética Fenotipo Psicotropo Estimulante SNC Orina Enzima Oxidoreductases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17743636
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1097/01.fpc.0000204994.99429.46 
https://dx.doi.org/10.1097/01.fpc.0000204994.99429.46
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