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Selective kinase inhibition with daily imatinib intensifies toxicity of chemotherapy in patients with solid tumours

Author
GEORGE, Suzanne1 ; DESAI, Jayesh1 ; EDER, J. Paul1 ; MANOLA, Judith1 ; RYAN, David P1 ; APPLEMAN, Leonard J1 ; DEMETRI, George D1
[1] Dana-Farber Cancer Institute, Massachusetts General Hospital, Ludwig Center for Cancer Research at Dana-Farber/Haruard, Harvard Medical School, Boston, MA, United States
Source

European journal of cancer (1990). 2006, Vol 42, Num 7, pp 864-870, 7 p ; ref : 47 ref

ISSN
0959-8049
Scientific domain
Medical oncology; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Chemotherapy Clinical trial Kinase inhibition Targeted therapy
Keyword (fr)
Anticancéreux Cancérologie Chimiothérapie Ciblage Essai clinique Homme Imatinib Inhibiteur enzyme Kinase Pharmacologie Protein-tyrosine kinase Toxicité Traitement Tumeur solide Inhibiteur tyrosine kinase Enzyme Transferases Tumeur maligne
Keyword (en)
Antineoplastic agent Cancerology Chemotherapy Targeting Clinical trial Human Imatinib Enzyme inhibitor Kinase Pharmacology Protein-tyrosine kinase Toxicity Treatment Solid tumor Enzyme Transferases Malignant tumor
Keyword (es)
Anticanceroso Cancerología Quimioterapia Blancado Ensayo clínico Hombre Imatinib Inhibidor enzima Kinase Farmacología Protein-tyrosine kinase Toxicidad Tratamiento Tumor sólido Enzima Transferases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
General pharmacology Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17772274

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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