Molecular analysis of single B cells from T-cell-rich B-cell lymphoma shows the derivation of the tumor cells from mutating germinal center B cells and exemplifies means by which immunoglobulin genes are modified in germinal center B cells
- Author
- BRÄUNINGER, A; KÜPPERS, R; SPIEKER, T; SIEBERT, R; STRICKLER, J. G; SCHLEGELBERGER, B; RAJEWSKY, K; HANSMANN, M.-L
Department of Human Genetics, University of Kiel, Kiel, Germany
Department of Pathology, Mayo Clinic, Rochester, MN, United States
Department of Pathology, University of Frankfurt, Frankfurt, Germany
Institute for Genetics, University of Cologne, Cologne, Germany - Source
Blood. 1999, Vol 93, Num 8, pp 2679-2687 ; ref : 55 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- The Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Carcinogenèse Centre germinatif Diffus Gène Homme Immunoglobuline Lymphocyte B Lymphocyte T Lymphome grande cellule Réarrangement génique Transformation cellulaire Type histologique Gène V Lymphome lymphocyte b riche en lymphocyte T Hémopathie maligne Lymphome non hodgkinien Lymphoprolifératif syndrome
- Keyword (en)
- Carcinogenesis Germinative center Diffuse Gene Human Immunoglobulins B-Lymphocyte T-Lymphocyte Large cell lymphoma Gene rearrangement Cell transformation Histological type Malignant hemopathy Non Hodgkin lymphoma Lymphoproliferative syndrome
- Keyword (es)
- Carcinogénesis Centro germinativo Difuso Gen Hombre Inmunoglobulina Linfocito B Linfocito T Linfoma célula grande Redisposición génica Transformación celular Tipo histológico Hemopatía maligna Linfoma no Hodgkin Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1783432
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood.V93.8.2679 
https://dx.doi.org/10.1182/blood.V93.8.2679
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