Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders : evidence from a mouse model of Krabbe leukodystrophy
- Author
- TAYLOR, Roseanne M1 ; PYO LEE, Jean2 3 ; PALACINO, James J3 ; BOWER, Kate A3 ; JIANXUE LI3 ; VANIER, Marie T4 5 ; WENGER, David A6 ; SIDMAN, Richard L3 ; SNYDEI, Evan Y2 3
[1] Department of Animal Science, Faculty of Veterinary Science, University of Sydney and New South Wales, Australia
[2] Program in Stem Cells and Regeneration, Burnham Institute for Medical Research, La Jolla, California, United States
[3] Department of Neurology, Beth Israel Deaconess Medical Center and Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States
[4] INSEAM 189, Lyon-Sud Medical School, Oullins, France
[5] Fondation Gillet-Mérieux, Lyon-Sud Hospital, Pierre-Bénite, France
[6] Department of Neurology, Jefferson Medical College, Philadelphia, Pennsylvania, United States - Source
Journal of neurochemistry. 2006, Vol 97, Num 6, pp 1585-1599, 15 p ; ref : 1 p.1/4
- CODEN
- JONRA9
- ISSN
- 0022-3042
- Scientific domain
- Cell biology, histology; Neurology; Physiology, morphology
- Publisher
- Blackwell, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- childhood neurodegenerative diseases gene therapy mouse and human neural stem cells myelination oligodendrocytes psychosine
- Keyword (fr)
- Cellule souche Endogène Galactosylceramidase Glycolipide Homme Leucodystrophie Main Modèle animal Myéline Métabolisme pathologie Métabolite Oligodendrocyte Physiopathologie Résistance Souris Trouble neurologique Encéphale pathologie Enzyme Glycosidases Hydrolases Maladie dégénérative Mammalia Névroglie O-Glycosidases Rodentia Système nerveux central pathologie Système nerveux pathologie Vertebrata
- Keyword (en)
- Stem cell Endogenous Galactosylceramidase Glycolipid Human Leukodystrophy Hand Animal model Myelin Metabolic diseases Metabolite Oligodendrocyte Pathophysiology Resistance Mouse Neurological disorder Cerebral disorder Enzyme Glycosidases Hydrolases Degenerative disease Mammalia Neuroglia O-Glycosidases Rodentia Central nervous system disease Nervous system diseases Vertebrata
- Keyword (es)
- Célula primitiva Endógeno Galactosylceramidase Glicolípido Hombre Leucodistrofia Mano Modelo animal Mielina Metabolismo patología Metabolito Oligodendrocito Fisiopatología Resistencia Ratón Trastorno neurológico Encéfalo patología Enzima Glycosidases Hydrolases Enfermedad degenerativa Mammalia Neuroglia O-Glycosidases Rodentia Sistema nervosio central patología Sistema nervioso patología Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25C Isolated neuron and nerve. Neuroglia
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology Vertebrates : nervous system and sense organs
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17848096
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1111/j.1471-4159.2006.03986.x 
https://dx.doi.org/10.1111/j.1471-4159.2006.03986.x
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