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Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain

Author
MARTIN, Pamela M1 ; GOPAL, Elangovan1 ; ANANTH, Sudha1 ; LINA ZHUANG1 ; ITAGAKI, Shiro1 ; PRASAD, Balakrishna M2 ; SMITH, Sylvia B3 ; PRASAD, Puttur D1 ; GANAPATHY, Vadivel1
[1] Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, Georgia, United States
[2] Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia, United States
[3] Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta, Georgia, United States
Source

Journal of neurochemistry. 2006, Vol 98, Num 1, pp 279-288, 10 p ; ref : 36 ref

CODEN
JONRA9
ISSN
0022-3042
Scientific domain
Cell biology, histology; Neurology; Physiology, morphology
Publisher
Blackwell, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
brain ketone bodies neuroenergetics neuron- specific expression sodium-coupled monocarboxylate transporter sodium-coupled transport
Keyword (fr)
Acide gras Captation Chaîne courte Encéphale Homme Immunofluorescence Lactate Neurone Protéine Rat Sodium Souris Substrat Transport biologique Transporteur monocarboxylate Lipide Mammalia Névroglie Rodentia Système nerveux central Vertebrata
Keyword (en)
Fatty acids Uptake Short chain Encephalon Human Immunofluorescence Lactates Neuron Protein Rat Sodium Mouse Substrate Biological transport Monocarboxylate transporter Lipids Mammalia Neuroglia Rodentia Central nervous system Vertebrata
Keyword (es)
Acido graso Captación Cadena corta Encéfalo Hombre Inmunofluorescencia Lactato Neurona Proteína Rata Sodio Ratón Substrato Transporte biológico Lípido Mammalia Neuroglia Rodentia Sistema nervioso central Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25B Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25D Central nervous system / 002A25D02 Biochemistry and metabolism

Discipline
Vertebrates : nervous system and sense organs
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17848384

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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