Single-dose bioavailability of levetiracetam intravenous infusion relative to oral tablets and multiple-dose pharmacokinetics and tolerability of levetiracetam intravenous infusion compared with placebo in healthy subjects
- Author
- RAMAEL, Steven1 ; DE SMEDT, Florence2 ; TOUBLANC, Nathalie2 ; OTOUL, Christian2 ; BOULANGER, Pierre2 ; RIETHUISEN, Jean-Michel2 ; STOCKIS, Armel2
[1] SGS Life Sciences Services, Research Unit Stuivenberg, Antwerp, Belgium
[2] UCB S.A, Braine l'Alleud, Belgium - Source
Clinical therapeutics. 2006, Vol 28, Num 5, pp 734-744, 11 p ; ref : 24 ref
- ISSN
- 0149-2918
- Scientific domain
- Pharmacology drugs
- Publisher
- Excerpta Medica, Belle Mead, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- antiepileptic drugs epilepsy intravenous levetiracetam pharmacokinetics
- Keyword (fr)
- Anticonvulsivant Biodisponibilité Comprimé Dose répétée Dose unique Epilepsie Etude comparative Homme Individu sain Infusion Lévétiracétam Médicament Nootrope Perfusion Pharmacocinétique Placebo Psychotrope Toxicité Voie intraveineuse Voie orale Encéphale pathologie Forme pharmaceutique Système nerveux central pathologie Système nerveux pathologie
- Keyword (en)
- Anticonvulsant Bioavailability Tablet Multiple dose Single dose Epilepsy Comparative study Human Healthy subject Infusion Levetiracetam Drug Nootropic agent Perfusion Pharmacokinetics Placebo Psychotropic Toxicity Intravenous administration Oral administration Cerebral disorder Dosage form Central nervous system disease Nervous system diseases
- Keyword (es)
- Anticonvulsivante Biodisponibilidad Tableta Dosis múltiple Dosis única Epilepsia Estudio comparativo Hombre Individuo sano Infusión Levetiracetam Medicamento Nootropo Perfusión Farmacocinética Placebo Psicotropo Toxicidad Vía intravenosa Vía oral Encéfalo patología Forma farmacéutica Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A03 Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
- Discipline
- General pharmacology Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17893933
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.clinthera.2006.05.004 
https://dx.doi.org/10.1016/j.clinthera.2006.05.004
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