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Myocardial distribution and biotransformation in vitro and in vivo of nicorandil in rats, with special reference to mitochondria

Author
SAKAI, K1 ; TSUCHIYA, Y1 ; KITAJIMA, S1 ; HAMADA, H1
[1] Central Research Laboratories, Chugai Pharmaceutical Co., Ltd., Takada, Toshima-ku, Tokyo, Japan
Source

Journal of cardiovascular pharmacology. 1999, Vol 33, Num 1, pp 163-168 ; ref : 27 ref

CODEN
JCPCDT
ISSN
0160-2446
Scientific domain
Cardiology, blood circulation, phlebology; Pharmacology drugs
Publisher
Lippincott, Hagerstown, MD / Lippincott, Philadelphia, PA
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Absorption Agoniste canal potassium Animal Antiangoreux Antiarythmique Appareil circulatoire Coeur Distribution In vitro In vivo Intracellulaire Microsome Mitochondrie Myocarde Mécanisme action Métabolisme Nicorandil Nitrate organique Pharmacocinétique Rat Vasodilatateur coronarien Voie orale Mammalia Rodentia Vertebrata
Keyword (en)
Absorption Potassium channel agonist Animal Antianginal agent Antiarrhythmic agent Circulatory system Heart Distribution In vitro In vivo Intracellular Microsome Mitochondria Myocardium Mechanism of action Metabolism Nicorandil Organic nitrate Pharmacokinetics Rat Coronary vasodilator agent Oral administration Mammalia Rodentia Vertebrata
Keyword (es)
Absorción Agonista canal potasio Animal Antianginoso Antiarrítmico Aparato circulatorio Corazón Distribución In vitro In vivo Intracelular Microsoma Mitocondria Miocardio Mecanismo acción Metabolismo Nicorandil Nitrato orgánico Farmacocinética Rata Vasodilatator coronario Vía oral Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F03 Antianginal agents. Coronary vasodilator agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1789618

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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