Overexpression of cyclo-oxygenase-2 is an independent predictor of unfavourable outcome in node-negative breast cancer, but is not associated with protein kinase B (Akt) and mitogen-activated protein kinase (ERK1/2, p38) activation or with her-2/neu siqnallinq pathways
- Author
- SCHMILZ, K. J1 ; CALLIES, R2 ; WOHLSCHLAEGER, J1 ; KIMMIG, R2 ; OTTERBACH, F1 ; BOHR, J1 ; LEE, H.-S1 ; TAKEDA, A3 ; SCHMID, K. W1 ; BABA, H. A
[1] Institute of Pathology, University Hospital of Essen, Essen, Germany
[2] Department of Obstetrics and Gynaecology, University Hospital of Essen, Germany
[3] Department of Internal Medicine, Gumma Paz Gakuen College, Gumma, Japan - Source
Journal of clinical pathology. 2006, Vol 59, Num 7, pp 685-691, 7 p ; ref : 43 ref
- CODEN
- JCPAAK
- ISSN
- 0021-9746
- Scientific domain
- Medical oncology; Medical laboratory techniques; General medicine general surgery
- Publisher
- BMJ, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activation Akt protein kinase Anatomopathologie Association Evolution Facteur prédictif Gène erbB2 Gène onc cellulaire Mitogen-activated protein kinase Oxygenase Pronostic Protooncogène Prédiction Surexpression génique Cancer sein Extracellular signal-regulated protein kinase 1 Extracellular signal-regulated protein kinase 2 Enzyme Glande mammaire pathologie Oxidoreductases Tumeur maligne
- Keyword (en)
- Activation Akt protein kinase Anatomic pathology Association Evolution Predictive factor erbB2 Gene C-Onc gene Mitogen-activated protein kinase Oxygenase Prognosis Protooncogene Prediction Gene overexpression Breast cancer Extracellular signal-regulated protein kinase 1 Extracellular signal-regulated protein kinase 2 Enzyme Mammary gland diseases Oxidoreductases Malignant tumor
- Keyword (es)
- Activación Akt protein kinase Anatomía patológica Asociación Evolución Factor predictivo Gen erbB2 Gen onc celular Mitogen-activated protein kinase Oxygenase Pronóstico Protooncogen Predicción Sobreexpressión genética Cáncer pecho Enzima Glándula mamaria patología Oxidoreductases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20E Mammary gland diseases / 002B20E02 Tumors
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B24 Investigative techniques, diagnostic techniques (general aspects) / 002B24O Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
- Discipline
- Gynecology. Andrology. Obstetrics Scanning and diagnostic techniques
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 17901141
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1136/jcp.2005.030650 
https://dx.doi.org/10.1136/jcp.2005.030650
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