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Monitoring CML patients responding to treatment with tyrosine kinase inhibitors : review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results

Author
HUGHES, Timothy; DEININGER, Michael; GABERT, Jean; GRIMWADE, David; HEHLMANN, Rüdiger; KAMEL-REID, Suzanne; LIPTON, Jeffrey H; LONGTINE, Janina; MARTINELLI, Giovanni; SAGLIO, Giuseppe; SOVERINI, Simona; STOCK, Wendy; HOCHHAUS, Andreas; GOLDMAN, John M; BRANFORD, Susan; RADICH, Jerald; KAEDA, Jaspal; BACCARANI, Michele; CORTES, Jorge; CROSS, Nicholas C. P; DRUKER, Brian J
[1] Institute of Medical and Veterinary Science, Adelaide, Australia
[2] Department of Hematology/Medical Oncology, Oregon Health & Science University Cancer Institute, Portland, OR, United States
[3] Faculty of Clinical Medicine Mannheim, University of Heidelberg, Mannheim, Germany
[4] Fred Hutchinson Cancer Research Center, Seattle, WA, United States
[5] Department of Haematology, Imperial College at Hammersmith Hospital, London, United Kingdom
[6] Institute of Hematology and Medical Oncology Seragnoli, University of Bologna, Italy
[7] Department of Leukemia, The University of Texas, M. D. Anderson Cancer Center, Houston, TX, United States
[8] National Genetics Reference Laboratory, University of Southampton, Salisbury, United Kingdom
[9] Assistance Publique des Hopitaux de Marseille (APHM) and Equipe de Recherche Technologique (ERT), University de la Mediterranée, Marseille, France
[10] Department of Medical and Molecular Genetics, King's College, London, United Kingdom
[11] Department of Medical Oncology and Hematology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
[12] Department of Pathology, Brigham and Women's Hospital, Boston, MA, United States
[13] Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy
[14] Department of Medicine, University of Chicago, Chicago, IL, United States
[15] Hematology Branch, National Heart, Lung & Blood Institute, National Institutes of Health (NIH), Bethesda, MD, United States
Source

Blood. 2006, Vol 108, Num 1, pp 28-37, 10 p ; ref : 82 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
The Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Article synthèse Chromosome Ph1 Chronique Expression génique Gène hybride Homme Inhibiteur protéique Leucémie myéloïde Maladie résiduelle imperceptible Protein-tyrosine kinase Protéine fusion Réaction chaîne polymérase Surveillance Temps réel Gène BCR-ABL Aberration chromosomique Chromosome anormal Enzyme Hémopathie maligne Myéloprolifératif syndrome Transferases
Keyword (en)
Review Philadelphia chromosome Chronic Gene expression Hybrid gene Human Protein inhibitor Chronic myelocytic leukemia Minimal residual disease Protein-tyrosine kinase Fusion protein Polymerase chain reaction Surveillance Real time Chromosomal aberration Abnormal chromosome Enzyme Malignant hemopathy Myeloproliferative syndrome Transferases
Keyword (es)
Artículo síntesis Cromosoma Ph1 Crónico Expresión genética Gen híbrido Hombre Inhibidor proteico Leucemia mieloidea Enfermedad residual imperceptible Protein-tyrosine kinase Proteína fusionada Reacción cadena polimerasa Vigilancia Tiempo real Aberración cromosómica Cromosoma anormal Enzima Hemopatía maligna Mieloproliferativo síndrome Transferases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17934557

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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