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Discrimination between ribonuclease H- and ribonuclease L-mediated RNA degradation by 2'-O-methylated 2-5A-antisense oligonucleotides

Author
CRAMER, H1 ; PLAYERS, M. R1 ; TORRENCE, P. F1
[1] Section on Biomedical Chemistry, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0805, United States
Source

Bioorganic & medicinal chemistry letters (Print). 1999, Vol 9, Num 7, pp 1049-1054 ; ref : 13 ref

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Calf thymus ribonuclease H DNA antisens Dégradation enzymatique Oligodésoxyribonucléotide Oligonucléotide antisens Ribonuclease Bras espaceur Enzyme Esterases Hydrolases
Keyword (en)
Calf thymus ribonuclease H Antisense DNA Enzymatic digestion Oligodeoxyribonucleotide Antisense oligonucleotide Ribonuclease Spacer arm Enzyme Esterases Hydrolases
Keyword (es)
Calf thymus ribonuclease H DNA antisentido Degradación enzimática Oligodesoxirribonucleótido Oligonucleótido antisentido Ribonuclease Enzima Esterases Hydrolases
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02C Nucleic acids / 002A02C04 Rna, ribonucleoproteins

Discipline
Analytical, structural and metabolic biochemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1794794

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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