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Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel

Author
BEITELSHEES, Amber L1 ; MCLEOD, Howard L2 ; MORENO, Raul4 ; ESCANED, Javier4 ; ALFONSO, Fernando4 ; BANUELOS, Camino4 ; COSTA, Marco A3 ; BASS, Theodore A3 ; PIGNATTI, Pier Franco5 ; MACAYA, Carlos4 ; ANGIOLILLO, Dominick J3 ; FERNANDEZ-ORTIZ, Antonio4 ; BERNARDO, Esther4 ; RAMIREZ, Celia4 ; CAVALLARI, Ugo5 ; TRABETTI, Elisabetta5 ; SABATE, Manel4 ; HERNANDEZ, Rosana4
[1] Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, Mo, United States
[2] Division of Oncology and Departments of Genetics and Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Mo, United States
[3] Division of Cardiology, University of Florida, Shands Jacksonville, United States
[4] Cardiovascular Institute, San Carlos University Hospital, Madrid, Spain
[5] Department of Mother and Child & Biology-Genetics, University of Verona, Italy
Source

Arteriosclerosis, thrombosis, and vascular biology. 2006, Vol 26, Num 8 ; 1681-1683,1895-1900 [9 p.] ; ref : 33 ref

CODEN
ATVBFA
ISSN
1079-5642
Scientific domain
Cardiology, blood circulation, phlebology
Publisher
Lippincott, Hagerstown, MD / Lippincott, Philadelphia, PA
Publication country
United States
Document type
Article
Language
English
Author keyword
clopidogrel platelet polymorphism
Keyword (fr)
Appareil circulatoire pathologie Athérosclérose Clopidogrel Cytochrome P450 Foie Inhibiteur thromboagrégation Polymorphisme Séquence nucléotide Thrombocyte Variabilité Appareil digestif Enzyme Thiénopyridine dérivé Vaisseau sanguin pathologie
Keyword (en)
Cardiovascular disease Atherosclerosis Clopidogrel Cytochrome P450 Liver Antiplatelet agent Polymorphism Nucleotide sequence Platelet Variability Digestive system Enzyme Thienopyridine derivative Vascular disease
Keyword (es)
Aparato circulatorio patología Ateroesclerosis Clopidogrel Citocromo P450 Hígado Inhibidor tromboagregación Polimorfismo Secuencia nucleótido Trombocito Variabilidad Aparato digestivo Enzima Thienopyridin derivado Vaso sanguíneo patología
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A03 Coronary heart disease

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12B Blood and lymphatic vessels / 002B12B01 Atherosclerosis (general aspects, experimental research)

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12B Blood and lymphatic vessels / 002B12B03 Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B24 Investigative techniques, diagnostic techniques (general aspects) / 002B24C Ultrasonic investigative techniques / 002B24C01 Cardiovascular system

Discipline
Cardiology. Circulatory system Scanning and diagnostic techniques
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
17984150

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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