Computational elucidation of the structural basis of ligand binding to the dopamine 3 receptor through docking and homology modeling
- Author
- HOBRATH, Judith Varady; SHAOMENG WANG
[1] Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48109-0934, United States - Source
Journal of medicinal chemistry (Print). 2006, Vol 49, Num 15, pp 4470-4476, 7 p ; ref : 75 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amine tertiaire Fixation ligand Homologie In vitro Modèle moléculaire Modélisation Naphtalène dérivé Phénols Prédiction Relation structure activité Récepteur dopaminergique D3 Synthèse chimique Naphtol(7-dipropylamino-5,6,7,8-tétrahydro) Pipéridine(3-aryl-1-propyl)
- Keyword (en)
- Tertiary amine Ligand binding Homology In vitro Molecular model Modeling Naphthalene derivatives Phenols Prediction Structure activity relation D3 Dopamine receptor Chemical synthesis
- Keyword (es)
- Amina terciaria Fijación ligando Homología In vitro Modelo molecular Modelización Naftaleno derivado Fenoles Predicción Relación estructura actividad Receptor dopaminérgico D3 Síntesis química
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09A Catecholaminergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18001537
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm0501634 
https://dx.doi.org/10.1021/jm0501634
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