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Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT) : Influence of steroidal hydroxylation pattern and C-24 conjugation

Author
BALAKRISHNAN, Anand1 ; WRING, Stephen A2 ; POLLI, James E1
[1] Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, HSF2, Room 623, 20 Penn Street, Baltimore, Maryland 21201, United States
[2] Trimeris Inc, Morrisville, North Carolina 27560, United States
Source

Pharmaceutical research. 2006, Vol 23, Num 7, pp 1451-1459, 9 p ; ref : 19 ref

CODEN
PHREEB
ISSN
0724-8741
Scientific domain
Pharmacology drugs
Publisher
Springer, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
ASBT QSAR SLC10A2 bile acid prodrug transporter
Keyword (fr)
Acide biliaire Conjugaison Homme Hydroxylation Interaction Promédicament Protéine transport Relation structure activité Technologie pharmaceutique Métabolisme Pharmacocinétique
Keyword (en)
Bile acid Conjugation Human Hydroxylation Interaction Prodrug Carrier protein Structure activity relation Pharmaceutical technology Metabolism Pharmacokinetics
Keyword (es)
Acido biliar Conjugación Hombre Hidroxilación Interacción Promedicamento Proteína transportador Relación estructura actividad Tecnología farmacéutica Metabolismo Farmacocinética
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18005241

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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