Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure-safety relationship in patients with non-small cell lung cancer
- Author
- LU, Jian-Feng; EPPLER, Steve M; WOLF, Julie; HAMILTON, Marta; RAKHIT, Ashok; BRUNO, Rene; LUM, Bert L
[1] Pharmacokinetic and Pharmacodynamic Sciences, Genentech, South San Francisco, United States
[2] OSI Pharmaceuticals, Boulder, United States
[3] F. Hoffmann-La Roche, Nutley, United States - Source
Clinical pharmacology and therapeutics. 2006, Vol 80, Num 2, pp 136-145, 10 p ; ref : 33 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Cancer du poumon Carcinome non petite cellule bronchopulmonaire Erlotinib Exposition Homme Pharmacocinétique Toxicité Tumeur solide Inhibiteur de la tyrosine kinase Appareil respiratoire pathologie Bronche pathologie Enzyme Inhibiteur enzyme Poumon pathologie Protein-tyrosine kinase Quinazoline dérivé Récepteur facteur croissance épiderme Transferases Tumeur maligne
- Keyword (en)
- Antineoplastic agent Lung cancer non-small cell lung carcinoma Erlotinib Exposure Human Pharmacokinetics Toxicity Solid tumor Respiratory disease Bronchus disease Enzyme Enzyme inhibitor Lung disease Protein-tyrosine kinase Quinazoline derivatives Epidermal growth factor receptor Transferases Malignant tumor
- Keyword (es)
- Anticanceroso Cáncer del pulmón Carcinoma no pequeňa célula bronchopulmonar Erlotinib Exposición Hombre Farmacocinética Toxicidad Tumor sólido Aparato respiratorio patología Bronquio patología Enzima Inhibidor enzima Pulmón patología Protein-tyrosine kinase Receptor factor crecimiento epidermi Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- General pharmacology Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18053889
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.clpt.2006.04.007 
https://dx.doi.org/10.1016/j.clpt.2006.04.007
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