Bridging chemical and biological space : Target fishing using 2D and 3D molecular descriptors
- Author
- NETTLES, James H1 ; JENKINS, Jeremy L1 ; BENDER, Andreas1 ; ZHAN DENG1 ; DAVIES, John W1 ; GLICK, Meir1
[1] Lead Discovery Informatics, Lead Discovery Center, Novartis Institutes for BioMedical Research Inc., 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States - Source
Journal of medicinal chemistry (Print). 2006, Vol 49, Num 23, pp 6802-6810, 9 p ; ref : 55 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Ligand Modèle 2 dimensions Modèle 3 dimensions Modèle moléculaire Modélisation Protein kinase Prédiction Relation structure activité Récepteur hormonal Récepteur oestrogène Récepteur rétinoïde RXR Transduction signal Enzyme Transferases
- Keyword (en)
- Ligand Two dimensional model Three dimensional model Molecular model Modeling Protein kinase Prediction Structure activity relation Hormonal receptor Estrogen receptor RXR retinoid receptor Signal transduction Enzyme Transferases
- Keyword (es)
- Ligando Modelo 2 dimensiones Modelo 3 dimensiones Modelo molecular Modelización Protein kinase Predicción Relación estructura actividad Receptor hormonal Receptor estrógeno Receptor retinoide RXR Transducción señal Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18270984
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm060902w 
https://dx.doi.org/10.1021/jm060902w
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