Regiospecific N9 alkylation of 6-(heteroaryl)purines : Shielding of N7 by a proximal heteroaryl C-H
- Author
- MINGHONG ZHONG1 ; ROBINS, Morris J1
[1] Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602-5700, United States - Source
Journal of organic chemistry. 2006, Vol 71, Num 23, pp 8901-8906, 6 p
- CODEN
- JOCEAH
- ISSN
- 0022-3263
- Scientific domain
- Biochemistry, molecular biology, biophysics; Organic chemistry
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Agent alkylant Alkylation Azole dérivé Base purique Chaîne latérale Chlore composé organique Conformation DMF Diffraction RX Encombrement stérique Hétérocycle azote Imidazole dérivé Iode composé organique Protection Purine dérivé Régiospécificité Sodium hydrure Synthèse chimique
- Keyword (en)
- Alkylating agent Alkylation Azole derivatives Purine base Side chain Organic chlorine compounds Conformation N,N-Dimethylformamide X ray diffraction Steric hindrance Nitrogen heterocycle Imidazole derivatives Organic iodine compounds Protection Purine derivatives Regiospecificity Sodium hydride Chemical synthesis
- Keyword (es)
- Agente alquilante Alquilación Azol derivado Base púrica Cadena lateral Conformación Dimetilformamida Difracción RX Embarazo estérico Heterociclo nitrógeno Imidazol derivado Protección Purina derivado Regiospecificidad Sodio hidruro Síntesis química
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06B Heterocyclic compounds with only one n hetero atom and condensed derivatives
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06C Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18271078
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jo061759h 
https://dx.doi.org/10.1021/jo061759h
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