Metal complexes with superoxide dismutase-like activity as candidates for anti-prion drug
- Author
- FUKUUCHI, Tomoko1 2 ; DOH-URA, Katsumi3 ; YOSHIHARA, Shinichi2 ; OHTA, Shigeru1
[1] Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan
[2] Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Koshingai, Hiro, Kure, Hiroshima 737-0112, Japan
[3] Graduate School of Medicine, Tohoku University, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan - Source
Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 23, pp 5982-5987, 6 p
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- 2,2'-Biquinoline Chelate Cimetidine Copper Metal complex Prion SOD activity TPEN
- Keyword (fr)
- Chélateur Cimétidine Cuivre complexe Fer complexe In vitro Inhibition Lignée cellulaire Manganèse complexe Prion maladie Protéine PrP Quinoléine dérivé Relation structure activité Souris Superoxide dismutase Sélectivité Biquinolyle dérivé Ethylènediamine(N,N,N,N-tétrakis[2-pyridylméthyl]) Lignée ScN2a Encéphale pathologie Enzyme Infection Maladie dégénérative Mammalia Métal transition Complexe Oxidoreductases Rodentia Système nerveux central pathologie Système nerveux pathologie Vertebrata
- Keyword (en)
- Chelating agent Cimetidine Copper complex Iron complex In vitro Inhibition Cell line Manganese complex Prion disease Prion protein Quinoline derivatives Structure activity relation Mouse Superoxide dismutase Selectivity Cerebral disorder Enzyme Infection Degenerative disease Mammalia Transition metal Complexes Oxidoreductases Rodentia Central nervous system disease Nervous system diseases Vertebrata
- Keyword (es)
- Quelante Cimetidina Cobre complejo Hierro complejo In vitro Inhibición Línea celular Manganeso complejo Prion enfermedad Protéina PrP Quinolina derivado Relación estructura actividad Ratón Superoxide dismutase Selectividad Encéfalo patología Enzima Infección Enfermedad degenerativa Mammalia Metal transición Complejo Oxidoreductases Rodentia Sistema nervosio central patología Sistema nervioso patología Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B11 Miscellaneous
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18275322
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2006.08.115 
https://dx.doi.org/10.1016/j.bmcl.2006.08.115
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