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Rapid microwave-assisted fluorination yielding novel 5'-deoxy -5 ' -fluorouridine derivatives

Author
PHUOC LE, H1 ; MÜLLER, Christa E1
[1] Pharmaceutical Sciences Bonn (PSB), Pharmaceutical Chemistry, Institute of Pharmacy, University of Bonn, Kreuzbergweg 26, 53115 Bonn, Germany
Source

Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 23, pp 6139-6142, 4 p

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
5'-Deoxy-5'-fluorouridine derivatives Fluorinated nucleosides Microwave
Keyword (fr)
Chauffage hyperfréquence Fluor 18 Fluor Composé organique Fluor Isotope Fluoration Ligand Marquage radioisotopique Pyrimidine dérivé Pyrimidine nucléoside Substitution nucléophile Tomographie émission positon Ammonium(tétrabutyl) fluorure Radiofluoration Uracile dérivé Uridine(5,5p-difluoro) Uridine(5p-fluoro)
Keyword (en)
Microwave heating Fluorine 18 Fluorine Organic compounds Fluorine Isotopes Fluorination Ligand Radiolabelling Pyrimidine derivatives Pyrimidine nucleoside Nucleophilic substitution Positron emission tomography
Keyword (es)
Calentamiento hiperfrecuencia Fluor Compuesto orgánico Fluor Isótopo Fluoración Ligando Marcación radioisotópica Pirimidina derivado Pirimidina nucleósido Substitución nucleófila Tomografía emisión positrones
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C07 Carbohydrates. Nucleosides and nucleotides / 001C03C07B Nucleosides, nucleotides and oligonucleotides

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02T Contrast media. Radiopharmaceuticals

Discipline
Organic chemistry Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18275354

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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