Direct separation of labetalol stereoisomers in a high performance liquid chromatography system using helically self-assembled chelate as chiral selector in the mobile phase
- Author
- BAZYLAK, G1 ; ABOUL-ENEIN, H. Y2
[1] Department of General Chemistry, Institute of Physiology and Biochemistry, Medical University of Lodz, Lindleya 6, 90-131 Lodz, Poland
[2] Bioanalytical and Drug Development Laboratory, Biological and Medical Research Department, MBC-03, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia - Source
Journal of liquid chromatography & related technologies. 1999, Vol 22, Num 8, pp 1171-1192 ; ref : 62 ref
- CODEN
- JLCTFC
- ISSN
- 1082-6076
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry
- Publisher
- Taylor & Francis, Colchester
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aminoalcool Antiarythmique Antihypertenseur Benzamide dérivé Bloquant α-adrénergique Bloquant β-adrénergique Chiralité Chromatographie HPLC Chromatographie phase inverse Composition phase Condition isocratique Coordinat organique Dédoublement optique Détecteur UV Détecteur fluorescence Enaminone Enantiomère Labétalol Modèle 3 dimensions Modèle moléculaire Modélisation Mécanisme Nickel II Complexe Phase mobile Reconnaissance Structure supramoléculaire Sélecteur chiral Séparation
- Keyword (en)
- Aminoalcohol Antiarrhythmic agent Antihypertensive agent Benzamide derivatives Alpha blocking agent Beta blocking agent Chirality HPLC chromatography Reversed phase chromatography Phase composition Isocratic condition Organic ligand Optical resolution Ultraviolet detector Fluorescence detector Enaminone Enantiomer Labetalol Three dimensional model Molecular model Modeling Mechanism Nickel II Complexes Mobile phase Recognition Supramolecular structure Chiral selector Separation
- Keyword (es)
- Aminoalcohol Antiarrítmico Antihipertensivo Benzamida derivado Bloqueador α-adrenérgico Bloqueador β-adrenérgico Quiralidad Cromatografía HPLC Cromatografía fase inversa Composición fase Condición isocrática Ligando orgánico Desdoblamiento óptico Detector UV Detector fluorescencia Enaminona Enantiómero Labetalol Modelo 3 dimensiones Modelo molecular Modelización Mecanismo Niquel II Complejo Fase móvil Reconocimiento Estructura supramolecular Selector quiral Separación
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1833589
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1081/JLC-100101725 
https://dx.doi.org/10.1081/JLC-100101725
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