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Radiosynthesis of 3-(3-[18F]fluoropropoxy )-4-(benzyloxy)-N-[(1 -dimethylaminocyclopentyl)methyl ]-5-methoxybenzamide, a potential PET radiotracer for the glycine transporter GlyT-2

Author
HAIBIN TIAN; VOGEL, Rebecca; AMICI, Louis; TAMAGNAN, Gilles; BALDWIN, Ronald M
[1] Departments of Psychiatry and Diagnostic Radiology, Yale University School of Medicine, Yale-VA Positron Emission Tomography Center, Veterans Affairs Medical Center, West Haven, CT, United States
Source

Journal of labelled compounds & radiopharmaceuticals. 2006, Vol 49, Num 14, pp 1247-1258, 12 p ; ref : 18 ref

ISSN
0362-4803
Scientific domain
Biochemistry, molecular biology, biophysics; Organic chemistry; Pharmacology drugs
Publisher
Wiley, Chichester / Wiley, New York, NY
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
PET fluorine-18 glycine transporter 2(GlyT2) radiotracer transporter 2(GlyT2)
Keyword (fr)
Agent scintigraphique Amine tertiaire Carboxamide Composé benzénique Ether Fluor 18 Fluor Isotope Fluoration Ligand Marquage radioisotopique Produit radioisotopique Synthèse chimique Benzamide(4-benzyloxy-N-[(1-[diméthylamino]cyclopentyl)méthyl]-3-[3-fluoropropoxy]-5-méthoxy) Cyclopentane(1-aminométhyl-1-diméthylamino) Gallique acide ester méthyle Propane-1,3-diol ditosylate Radiosynthèse Transporteur glycine GLYT2
Keyword (en)
Scintigraphic agent Tertiary amine Carboxamide Benzenic compound Ether Fluorine 18 Fluorine Isotopes Fluorination Ligand Radiolabelling Radiopharmaceuticals Chemical synthesis GLYT2 glycine transporter
Keyword (es)
Agente centelleográfico Amina terciaria Carboxamida Compuesto bencénico Eter Fluor Isótopo Fluoración Ligando Marcación radioisotópica Producto radioisotópico Síntesis química
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02T Contrast media. Radiopharmaceuticals

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18409799

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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