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Clot structure modification by fondaparinux and consequence on fibrinolysis : A new mechanism of antithrombotic activity

Author
VARIN, Rémi1 ; MIRSHAHI, Shahsultan2 ; SORIA, Jeannette3 4 ; MIRSHAHI, Pezhman1 2 3 4 ; KIERZEK, Gerald5 ; SEBAOUN, David3 4 ; MISHAL, Zohar6 ; VANNIER, Jean-Pierre1 ; BORG, Jeanne Yvonne1 ; SIMONEAU, Guy7 ; SORIA, Claudine1
[1] Groupe de Recherche MERCI, EA 3829, Faculté de Médecine et de Pharmacie, Boulevard Gambetta, Rouen, France
[2] Stago R&D, Gennevilliers, France
[3] INSERM, UMR763, IFR 58, Université Pierre et Marie Curie, Paris, France
[4] Laboratoire d'Onco-Hématologie de l'Hôtel Dieu de Paris, Paris, France
[5] Emergency Department, APHP-Hôtel Dieu de Paris, Paris, France
[6] Laboratoire de Cytométrie de flux, CNRS, Villejuif, France
[7] Unité de Recherche Clinique, Hôpital Lariboisière, Paris, France
Source

Thrombosis and haemostasis. 2007, Vol 97, Num 1, pp 27-31, 5 p ; ref : 25 ref

CODEN
THHADQ
ISSN
0340-6245
Scientific domain
Cardiology, blood circulation, phlebology; Hematology
Publisher
Schattauer, Stuttgart
Publication country
Germany
Document type
Article
Language
English
Author keyword
Fondaparinux clot structure fibrin network fibrinolysis
Keyword (fr)
Activité biologique Antithrombotique Caillot Coagulation Factor Xa Coagulation sanguine Fibrine Fibrinolyse Fondaparinux sodique Inhibiteur enzyme Modification structure Mécanisme Réseau Structure Enzyme Hydrolases Pentaoside Peptidases Serine endopeptidases
Keyword (en)
Biological activity Antithrombotic agent Clot Coagulation Factor Xa Blood coagulation Fibrin Fibrinolysis Fondaparinux sodium Enzyme inhibitor Structure modification Mechanism Network Structure Enzyme Hydrolases Pentasaccharide Peptidases Serine endopeptidases
Keyword (es)
Actividad biológica antitrombōtico Coágulo Coagulation Factor Xa Coagulación sanguínea Fibrina Fibrinólisis Fondaparinux sódico Inhibidor enzima Modificación estructural Mecanismo Red Estructura Enzima Hydrolases Pentaholósido Peptidases Serine endopeptidases
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04I Blood coagulation. Blood cells

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19C Platelet diseases and coagulopathies

Discipline
Blood diseases Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18418869

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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