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Interaction of valerian extracts of different polarity with adenosine receptors : Identification of isovaltrate as an inverse agonist at A1 receptors

Author
LACHER, Svenja K1 ; MAYER, Ralf1 ; SICHARDT, Kathrin2 ; NIEBER, Karen2 ; MÜLLER, Christa E1
[1] Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany
[2] Institute of Pharmacy, Pharmacology for Nature Sciences, University Leipzig, Leipzig, Germany
Source

Biochemical pharmacology. 2007, Vol 73, Num 2, pp 248-258, 11 p ; ref : 34 ref

CODEN
BCPCA6
ISSN
0006-2952
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
Publisher
Elsevier Science, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
A1 antagonist Adenosine receptors Bioassay-guided fractionation Inverse agonist Isovaltrate Valerian
Keyword (fr)
Agoniste inverse Antagoniste Essai biologique Extrait Fractionnement Guidage Identification Interaction Polarité Récepteur adénosinique Récepteur biologique
Keyword (en)
Inverse agonist Antagonist Bioassay Extract Fractionation Guidance Identification Interaction Polarity Adenosine receptor Biological receptor
Keyword (es)
Agonista inversa Antagonista Prueba biológica Extracto Fraccionamiento Guiado Identificación Interacción Polaridad Receptor adenosínico Receptor biológico
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18430187

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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