Interaction of omeprazole with a methylated derivative of β-cyclodextrin : Phase solubility, NMR spectroscopy and molecular simulation
- Author
- FIGUEIRAS, Ana1 ; SARRAGUCA, J. M. G2 ; CARVALHO, Rui A3 ; PAIS, A. A. C. C2 ; VEIGA, Francisco J. B1
[1] Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, 3000-295, Coimbra, Portugal
[2] Department of Chemistry, Faculty of Sciences and Technology, University of Coimbra, Coimbra, Portugal
[3] NMR Spectroscopy Center, Department of Biochemistry, Faculty of Sciences and Technology, University of Coimbra, Coimbra, Portugal - Source
Pharmaceutical research. 2007, Vol 24, Num 2, pp 377-389, 13 p ; ref : 45 ref
- CODEN
- PHREEB
- ISSN
- 0724-8741
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- NMR spectroscopy cyclodextrin inclusion complex molecular dynamics omeprazole phase solubility studies
- Keyword (fr)
- Antisécrétoire Antiulcéreux Composé inclusion Cyclodextrine Interaction Méthylation Oméprazole Simulation Solubilité Spectrométrie RMN Technologie pharmaceutique β-Cyclodextrine Benzimidazole dérivé Enzyme H+/K+-exchanging ATPase Hydrolases Inhibiteur enzyme Inhibiteur pompe proton Propriété physicochimique
- Keyword (en)
- Antisecretory agent Antiulcer agent Inclusion compound Cyclodextrin Interaction Methylation Omeprazole Simulation Solubility NMR spectrometry Pharmaceutical technology β-Cyclodextrin Benzimidazole derivatives Enzyme H+/K+-exchanging ATPase Hydrolases Enzyme inhibitor Proton pump inhibitor Physicochemical properties
- Keyword (es)
- Antisecretorio Antiulceroso Compuesto inclusión Ciclodextrina Interacción Metilación Omeprazol Simulación Solubilidad Espectrometría RMN Tecnología farmacéutica β-Ciclodextrina Benzimidazol derivado Enzima H+/K+-exchanging ATPase Hydrolases Inhibidor enzima Inhibidor bomba protón Propiedad fisicoquímica
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18497370
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s11095-006-9161-8 
https://dx.doi.org/10.1007/s11095-006-9161-8
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