Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
- Author
- MACPHERSON, Lindsey J1 ; DUBIN, Adrienne E1 2 ; EVANS, Michael J1 ; MARR, Felix3 ; SCHULTZ, Peter G3 4 ; CRAVATT, Benjamin F1 3 ; PATAPOUTIAN, Ardem1 4
[1] Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, United States
[2] Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, United States
[3] Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States
[4] Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, United States - Source
Nature (London). 2007, Vol 445, Num 7127, pp 541-545, 5 p ; ref : 31 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Canal ionique Clic Cystéine Douleur Froid Modification Neurone Nociception Récepteur biologique Souris Stimulus nociceptif Système nerveux périphérique Température Facteur milieu Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Ionic channel Click Cysteine Pain Cold Modification Neuron Nociception Biological receptor Mouse Noxious stimulus Peripheral nervous system Temperature Environmental factor Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Canal iónico Clic Cisteína Dolor Frío Modificación Neurona Nocicepción Receptor biológico Ratón Estímulo nociceptivo Sistema nervioso periférico Temperatura Factor medio Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25F Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors
- Discipline
- Vertebrates : nervous system and sense organs
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18505680
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature05544 
https://dx.doi.org/10.1038/nature05544
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