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Factors affecting the formation of eutectic solid dispersions and their dissolution behavior

Author
VIPPAGUNTA, Sudha R1 ; ZEREN WANG2 ; HORNUNG, Stefanie3 ; KRILL, Steven L2
[1] Pharmaceutical and Analytical Development, Novartis Pharmaceutical Corporation, East Hanover, NJ 07936, United States
[2] Pharmaceutical R&D, Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT 06877, United States
[3] Pharmaceutical and Analytical Development, Novartis Pharmaceutical Corporation, Basel, Switzerland
Source

Journal of pharmaceutical sciences. 2007, Vol 96, Num 2, pp 294-304, 11 p ; ref : 27 ref

CODEN
JPMSAE
ISSN
0022-3549
Scientific domain
Pharmacology drugs
Publisher
American Pharmaceutical Association, Washington, DC / Wiley, Hoboken, NJ
Publication country
United States
Document type
Article
Language
English
Author keyword
eutectic hydrogen bonding monotectic partition coefficient phase diagrams polyethylene glycol poorly water- soluble drug solid dispersions specificinter- action water-soluble carrier
Keyword (fr)
Coefficient partage Comportement Composé hydrosoluble Diagramme phase Dispersion solide Dissolution Ethylène oxyde polymère Hydrosolubilité Liaison hydrogène Médicament Technologie pharmaceutique
Keyword (en)
Partition coefficient Behavior Water soluble compound Phase diagram Solid dispersion Dissolution Ethylene oxide polymer Water solubility Hydrogen bond Drug Pharmaceutical technology
Keyword (es)
Coeficiente repartición Conducta Compuesto hidrosoluble Diagrama fase Dispersión sólida Disolución Etileno óxido polímero Hidrosolubilidad Enlace hidrógeno Medicamento Tecnología farmacéutica
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18512271

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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