Pharmacogenomic and structural analysis of constitutive G protein-coupled receptor activity
- Author
- SMIT, Martine J1 ; VISCHER, Henry F1 ; BAKKER, Remko A1 ; JONGEJAN, Aldo1 ; TIMMERMAN, Henk1 ; PARDO, Leonardo2 ; LEURS, Rob1
[1] Leiden/Amsterdam Center for Drug Research, Division of Medicinal Chemistry, Vrije Universiteit, Faculty of Sciences, Department of Chemistry, 1081 HV Amsterdam, Netherlands
[2] Laboratorio de Medicina Computacional, Unidad de Bioestadistica, Facultad de Medicina, Universidad Autonoma de Barcelona, Barcelona, Spain - Source
Annual review of pharmacology and toxicology. 2007, Vol 47, pp 53-87, 35 p ; ref : 200 ref
- ISSN
- 0362-1642
- Scientific domain
- Pharmacology drugs; Toxicology
- Publisher
- Annual Reviews, Palo Alto, CA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- constitutive activity; inverse agonism receptor motifs receptor structure
- Keyword (fr)
- Activité biologique Analyse structurale Article synthèse Homme Maladie Mutation ponctuelle Pharmacogénomique Relation structure activité Récepteur biologique Structure moléculaire Transduction signal Récepteur couplé protéine G
- Keyword (en)
- Biological activity Structural analysis Review Human Disease Point mutation Pharmacogenomics Structure activity relation Biological receptor Molecular structure Signal transduction G protein coupled receptor
- Keyword (es)
- Actividad biológica Análisis estructural Artículo síntesis Hombre Enfermedad Mutación puntual Farmacogenomica Relación estructura actividad Receptor biológico Estructura molecular Transducción señal Receptor acoplado proteína G
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18544883
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1146/annurev.pharmtox.47.120505.105126 
https://dx.doi.org/10.1146/annurev.pharmtox.47.120505.105126
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