Cinnabaramides A-G : Analogues of lactacystin and salinosporamide from a terrestrial streptomycete
- Author
- STADLER, Marc1 2 ; BITZER, Jens1 ; MAYER-BARTSCHMID, Anke2 ; MÜLLER, Hartwig2 ; BENET-BUCHHOLZ, Jordi3 ; GANTNER, Florian4 ; TICHY, Hans-Volker5 ; REINEMER, Peter6 ; BACON, Kevin B7
[1] InterMed Discovery GmbH (IMD), Otto-Hahn-Strasse 15, 44227 Dortmund, Germany
[2] Bayer Health Care, Pharma Division, P.O.B. 101709, 42096 Wuppertal, Germany
[3] Institut Català d'Investigació Química, 43007 Tarragona, Spain
[4] Boehringer Ingelheim, Birkendorfer Strasse 65, 88397 Biberach, Germany
[5] LUFA-ITL-GmbH, 24116 Kiel, Germany
[6] Proteros Biostructures GmbH, Am Klopferspitz 19, 82152 Martinsried, Germany
[7] Actimis Pharmaceuticals, 11099 North Torrey Pines Road, Suite 200, La Jolla, California 92037, United States - Source
Journal of natural products (Print). 2007, Vol 70, Num 2, pp 246-252, 7 p
- CODEN
- JNPRDF
- ISSN
- 0163-3864
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
/
American Society of Pharmacognosy, Glendale, AZ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Analyse structurale Anticancéreux Homme In vitro Inhibiteur Isolement Lactame Lactone Milieu marin Milieu terrestre Multicatalytic endopeptidase complex Origine microbienne Phylogenèse Production Pyrrolidine dérivé Spectrométrie RMN Streptomyces Structure cristalline Sélectivité Thioester 6-Oxa-2-azabicyclo[3.2.0]heptane-3,7-dione dérivé Cinnabaramide Cyclohexène dérivé Salinosporamide A Actinomycetales Actinomycetes Bactérie Enzyme Hydrolases Peptidases Streptomycetaceae
- Keyword (en)
- Biological activity Structural analysis Antineoplastic agent Human In vitro Inhibitor Isolation Lactam Lactone Marine environment Terrestrial environment Multicatalytic endopeptidase complex Microbial origin Phylogeny Production Pyrrolidine derivatives NMR spectrometry Streptomyces Crystalline structure Selectivity Thioester Actinomycetales Actinomycetes Bacteria Enzyme Hydrolases Peptidases Streptomycetaceae
- Keyword (es)
- Actividad biológica Análisis estructural Anticanceroso Hombre In vitro Inhibidor Aislamiento Lactamo Lactona Medio marino Medio terrestre Multicatalytic endopeptidase complex Origen microbiano Filogénesis Producción Espectrometría RMN Streptomyces Estructura cristalina Selectividad Tioester Actinomycetales Actinomycetes Bacteria Enzima Hydrolases Peptidases Streptomycetaceae
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05F Applied microbiology / 002A05F03 Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents / 002A05F03C Chemotherapic agents
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18606603
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/np060162u 
https://dx.doi.org/10.1021/np060162u
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