Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism
- Author
- WAN, X1 ; HARKAVY, B1 ; SHEN, N1 ; GROHAR, P1 ; HELMAN, L. J1
[1] Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, MD, United States - Source
Oncogene (Basingstoke). 2007, Vol 26, Num 13, pp 1932-1940, 9 p ; ref : 3/4 p
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Akt IGF-1R mTOR rapamycin rhabdomyosarcoma
- Keyword (fr)
- Activation Akt protein kinase Antibiotique Anticancéreux Carcinogenèse Immunodépresseur Mécanisme Rhabdomyosarcome Sirolimus Protein kinase mTOR Sarcome des tissus mous Muscle strié pathologie Tumeur maligne
- Keyword (en)
- Activation Akt protein kinase Antibiotic Antineoplastic agent Carcinogenesis Immunosuppressive agent Mechanism Rhabdomyosarcoma Sirolimus Soft tissue sarcoma Striated muscle disease Malignant tumor
- Keyword (es)
- Activación Akt protein kinase Antibiótico Anticanceroso Carcinogénesis Inmunodepresor Mecanismo Rabdomiosarcoma Sirolimús Sarcoma de tejidos blandos Músculo estriado patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B15 Diseases of the osteoarticular system / 002B15C Tumors of striated muscle and skeleton
- Discipline
- Molecular and cell biology Osteoarticular pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18622151
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1209990 
https://dx.doi.org/10.1038/sj.onc.1209990
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