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Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction

Author
HAORAH, James1 ; RAMIREZ, Servio H1 ; SCHALL, Kathy1 ; SMITH, Daniel1 ; PANDYA, Rita1 ; PERSIDSKY, Yuri1 2
[1] Center for Neurovirology and Neurodegenerative Disorders, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, United States
[2] Department of Pathology/Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States
Source

Journal of neurochemistry. 2007, Vol 101, Num 2, pp 566-576, 11 p ; ref : 2 p.1/4

CODEN
JONRA9
ISSN
0022-3042
Scientific domain
Cell biology, histology; Neurology; Physiology, morphology
Publisher
Blackwell, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
blood-brain barrier brain endothelial cell matrix metalloproteinases oxidative stress protein tyrosine kinase protein tyrosine phosphatase
Keyword (fr)
Accident cérébrovasculaire Barrière hématoencéphalique Cellule endothéliale Homme Lame basale Leucocyte Metalloendopeptidases Modèle Monocyte Oxygène Perméabilité Protein-tyrosine kinase Stress oxydatif Trouble fonctionnel cAMP-dependent protein kinase Appareil circulatoire pathologie Cérébrovasculaire pathologie Encéphale pathologie Enzyme Hydrolases Jonction cellulaire Peptidases Système nerveux central pathologie Système nerveux central Système nerveux pathologie Transferases Vaisseau sanguin pathologie
Keyword (en)
Stroke Blood brain barrier Endothelial cell Human Basement membrane Leukocyte Metalloendopeptidases Models Monocyte Oxygen Permeability Protein-tyrosine kinase Oxidative stress Dysfunction cAMP-dependent protein kinase Cardiovascular disease Cerebrovascular disease Cerebral disorder Enzyme Hydrolases Cell junction Peptidases Central nervous system disease Central nervous system Nervous system diseases Transferases Vascular disease
Keyword (es)
Accidente cerebrovascular Barrera hematoencefálica Célula endotelial Hombre Lámina basal Leucocito Metalloendopeptidases Modelo Monocito Oxígeno Permeabilidad Protein-tyrosine kinase Estrés oxidativo Trastorno funcional cAMP-dependent protein kinase Aparato circulatorio patología Vaso sanguíneo encéfalo patología Encéfalo patología Enzima Hydrolases Unión celular Peptidases Sistema nervosio central patología Sistema nervioso central Sistema nervioso patología Transferases Vaso sanguíneo patología
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A25 Vertebrates: nervous system and sense organs / 002A25B Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17C Vascular diseases and vascular malformations of the nervous system

Discipline
Neurology Vertebrates : nervous system and sense organs
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18635647

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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