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Rap1/B-raf signaling is activated in neuroendocrine tumors of the digestive tract and raf kinase inhibition constitutes a putative therapeutic target

Author
KARHOFF, Dorothee1 ; SAUER, Susanne1 ; SCHRADER, Jörg1 ; ARNOLD, Rudolf1 ; FENDRICH, Volker2 ; BARTSCH, Detlef K2 ; HÖRSCH, Dieter1
[1] Department of Internal Medicine, Division of Gastroenterology and Endocrinology, Philipps University Marburg, Marburg, Germany
[2] Department of Surgery, Philipps University Marburg, Marburg, Germany
Source

Neuroendocrinology (Basel). 2007, Vol 85, Num 1, pp 45-53, 9 p ; ref : 30 ref

CODEN
NUNDAJ
ISSN
0028-3835
Scientific domain
Endocrinology; Neurology
Publisher
Karger, Basel
Publication country
Switzerland
Document type
Article
Language
English
Author keyword
Extracellular signal-regulated kinase Neuroendocrine tumors Proliferation Apoptosis Protein kinase B Raf kinase Small G-proteins
Keyword (fr)
Akt protein kinase Apoptose Extracellular signal-regulated protein kinase Inhibition Kinase Multiplication cellulaire Protéine G Transduction signal Tumeur neuroendocrinienne Enzyme Mort cellulaire Transferases
Keyword (en)
Akt protein kinase Apoptosis Extracellular signal-regulated protein kinase Inhibition Kinase Cell proliferation G protein Signal transduction Neuroendocrine tumor Enzyme Cell death Transferases
Keyword (es)
Akt protein kinase Apoptosis Extracellular signal-regulated protein kinase Inhibición Kinase Multiplicación celular Proteína G Transducción señal Tumor neuroendocrino Enzima Muerte celular Transferases
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A28 Vertebrates: endocrinology

Discipline
Vertebrates : endocrinology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18648371

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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