Rational design of novel, potent small molecule pan-selectin antagonists
- Author
- KRANICH, Remo1 ; BUSEMANN, Anke S1 ; AYDT, Ewald M1 ; BOCK, Daniel1 ; SCHROETER-MAAS, Sabine1 ; BEYER, Diana1 ; HEINEMANN, Bo1 ; MEYER, Michael1 ; SCHIERHORN, Katrin1 ; ZAHLTEN, Rainer1 ; WOLFF, Gerhard1
[1] Revotar Biopharmaceuticals AG, Neuendorfstrasse 24a, 16761 Hennigsdorf, Germany - Source
Journal of medicinal chemistry (Print). 2007, Vol 50, Num 6, pp 1101-1115, 15 p ; ref : 36 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adhérence Antagoniste Antiinflammatoire Bimosiamose Cellule tumorale Homme In vitro Leucémie promyélocytaire Lignée HL60 Lignée cellulaire Modèle moléculaire Modélisation Molécule petite Phénols Protéine CAM Relation structure activité Synthèse chimique Sélectine Benzoïque acide(3,4,5-trihydroxy)
- Keyword (en)
- Adhesion Antagonist Antiinflammatory agent Bimosiamose Tumor cell Human In vitro Promyelocytic leukemia HL60 cell line Cell line Molecular model Modeling Small molecule Phenols Cell adhesion molecule Structure activity relation Chemical synthesis Selectin
- Keyword (es)
- Adherencia Antagonista Antiinflamatorio Bimosiamosa Célula tumoral Hombre In vitro Leucemia promielocítica Línea HL60 Línea celular Modelo molecular Modelización Molécula pequeña Fenoles Proteína CAM Relación estructura actividad Síntesis química Selectina
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02L Bones, joints and connective tissue. Antiinflammatory agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18652512
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm060536g 
https://dx.doi.org/10.1021/jm060536g
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