Comparison of inhibition potentials of drugs against zidovudine glucuronidation in rat hepatocytes and liver microsomes
- Author
- MANO, Yuji1 ; USUI, Takashi1 ; KAMIMURA, Hidetaka1
[1] Drug Metabolism Research Laboratories, Astellas Pharma Inc, Tokyo, Japan - Source
Drug metabolism and disposition. 2007, Vol 35, Num 4, pp 602-606, 5 p ; ref : 1/4 p
- CODEN
- DMDSAI
- ISSN
- 0090-9556
- Scientific domain
- Pharmacology drugs
- Publisher
- American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antirétroviral Antiviral Etude comparative Foie Glucuroconjugaison Hépatocyte In vitro Microsome Médicament Rat Zidovudine Analogue nucléoside Appareil digestif Didésoxynucléoside Enzyme Inhibiteur enzyme Inhibiteur reverse transcriptase Mammalia Métabolisme Nucleotidyltransferases Pharmacocinétique Pyrimidine nucléoside RNA-directed DNA polymerase Rodentia Transferases Vertebrata
- Keyword (en)
- Animal Antiretroviral agent Antiviral Comparative study Liver Glucuronic acid conjugation Hepatocyte In vitro Microsome Drug Rat Zidovudine Nucleoside analog Digestive system Dideoxynucleoside Enzyme Enzyme inhibitor Reverse transcriptase inhibitor Mammalia Metabolism Nucleotidyltransferases Pharmacokinetics Pyrimidine nucleoside RNA-directed DNA polymerase Rodentia Transferases Vertebrata
- Keyword (es)
- Animal Antiretroviral Antiviral Estudio comparativo Hígado Glucuroconjugación Hepatocito In vitro Microsoma Medicamento Rata Zidovudina Análogo nucleósido Aparato digestivo Didesoxinucleósido Enzima Inhibidor enzima Inhibitor reverse transcriptase Mammalia Metabolismo Nucleotidyltransferases Farmacocinética Pirimidina nucleósido RNA-directed DNA polymerase Rodentia Transferases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18656952
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1124/dmd.106.014225 
https://dx.doi.org/10.1124/dmd.106.014225
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