The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4
- Author
- KERR, Daniel J1 ; HAMEL, Ernest2 ; KATHERINE JUNG, M3 ; FLYNN, Bernard L1
[1] Department of Medicinal Chemistry, Faculty of Pharmacy, Monash University, 381 Royal Pde, Parkville, 3052, Australia
[2] Toxicology and Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, United States
[3] SAIC-Frederick, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, United States - Source
Bioorganic & medicinal chemistry. 2007, Vol 15, Num 9, pp 3290-3298, 9 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Chalcone Indanone Indenone Tubulin polymerisation inhibitor
- Keyword (fr)
- Anticancéreux Antimitotique Antitubuline Benzène dérivé Cellule tumorale Composé aromatique Composé bicyclique Cytotoxicité Cétone Enone Ether Flavonoïde Glande mammaire Homme In vitro Indane dérivé Indène dérivé Lignée cellulaire Phénols Relation structure activité Synthèse chimique Chalcone dérivé Combretastatine A4 analogue Indan-1-one dérivé Indén-1-one dérivé Lignée MCF7
- Keyword (en)
- Antineoplastic agent Antimitotic Antitubulin Benzene derivatives Tumor cell Aromatic compound Bicyclic compound Cytotoxicity Ketone Enone Ether Flavonoid Mammary gland Human In vitro Indan derivatives Indene derivatives Cell line Phenols Structure activity relation Chemical synthesis
- Keyword (es)
- Anticanceroso Antimitótico Antitubulina Benceno derivado Célula tumoral Compuesto aromático Compuesto bicíclico Citotoxicidad Cetona Enona Eter Flavonoide Glándula mamaria Hombre In vitro Indeno derivado Línea celular Fenoles Relación estructura actividad Síntesis química
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18658120
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2007.02.006 
https://dx.doi.org/10.1016/j.bmc.2007.02.006
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