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RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload

Author
CAVADINI, Patrizia1 ; BIASIOTTO, Giorgio1 ; POLI, Maura1 ; LEVI, Sonia2 ; VERARDI, Rosanna3 ; ZANELLA, Isabella1 ; DEROSAS, Manuela1 ; INGRASSIA, Rosaria1 ; CORRADO, Marcella1 ; AROSIO, Paolo1
[1] Dipartimento Materno Infantile e Tecnologie Biomediche, University of Brescia, Spedali Civili, Brescia, Italy
[2] Unit of Proteomics of Iron Metabolism, Vita e Salute San Raffaele University, Milan, Italy
[3] Section of Immunohematology and Transfusional Medicine, Spedali Civili, Brescia, Italy
Source

Blood. 2007, Vol 109, Num 8, pp 3552-3559, 8 p ; ref : 58 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
The Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Fer Hématologie Lignée HeLa Mitochondrie Phénotype RNA mitochondrial Silence expression génique Surcharge en fer Métabolisme pathologie
Keyword (en)
Iron Hematology Hela cell line Mitochondria Phenotype Mitochondrial RNA Gene silencing Iron overload Metabolic diseases
Keyword (es)
Hierro Hematología Célula HeLa Mitocondria Fenotipo ARN mitocondrial Silencio expresión genética Sobrecarga de hierro Metabolismo patología
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22E Other metabolic disorders / 002B22E03 Metals (hemochromatosis...)

Discipline
Blood diseases Metabolic diseases
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18690754

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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