Comparative analysis of epidermal growth factor receptor mutations and gene amplification as predictors of gefitinib efficacy in Japanese patients with nonsmall cell lung cancer
- Author
- SONE, Takashi1 ; KASAHARA, Kazuo1 ; KIMURA, Hideharu1 ; NISHIO, Kazuto2 ; MIZUGUCHI, Masayuki3 ; NAKATSUMI, Yasuto4 ; SHIBATA, Kazuhiko5 ; WASEDA, Yuko6 ; FUJIMURA, Masaki1 ; NAKAO, Shinji1
[1] Respiratory Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan
[2] Shien-Lab, National Cancer Center Hospital, Tokyo, Japan
[3] Respiratory Medicine, Ishikawa Prefectural Central Hospital, Kanazawa, Japan
[4] Respiratory Medicine, Kanazawa Municipal Hospital, Kanazawa, Japan
[5] Respiratory Medicine, Kouseiren Takaoka Hospital, Takaoka, Japan
[6] Department of Internal Medicine, Houju Kinen Hospital, Ishikawa, Japan - Source
Cancer. 2007, Vol 109, Num 9, pp 1836-1844, 9 p ; ref : 31 ref
- CODEN
- CANCAR
- ISSN
- 0008-543X
- Scientific domain
- Medical oncology
- Publisher
- Wiley-Liss, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Japanese epidermal growth factor receptor gene fluorescence in situ hybridization gefitinib gene amplification mutations
- Keyword (fr)
- Amplification génique Anticancéreux Cancer du poumon Cancérologie Carcinome non petite cellule bronchopulmonaire Efficacité traitement Etude comparative Facteur prédictif Gène Géfitinib Génétique Homme Hybridation in situ fluorescence Mutation Récepteur facteur croissance épiderme Récepteur facteur croissance Inhibiteur de la tyrosine kinase Japon Appareil respiratoire pathologie Bronche pathologie Enzyme Inhibiteur enzyme Poumon pathologie Protein-tyrosine kinase Quinazoline dérivé Transferases Tumeur maligne Asie
- Keyword (en)
- Gene amplification Antineoplastic agent Lung cancer Cancerology non-small cell lung carcinoma Treatment efficiency Comparative study Predictive factor Gene Gefitinib Genetics Human Fluorescence in situ hybridization Mutation Epidermal growth factor receptor Growth factor receptor Japan Respiratory disease Bronchus disease Enzyme Enzyme inhibitor Lung disease Protein-tyrosine kinase Quinazoline derivatives Transferases Malignant tumor Asia
- Keyword (es)
- Amplificación génica Anticanceroso Cáncer del pulmón Cancerología Carcinoma no pequeňa célula bronchopulmonar Eficacia tratamiento Estudio comparativo Factor predictivo Gen Gefitinib Genética Hombre Hibridación in situ fluorescencia Mutación Receptor factor crecimiento epidermi Receptor factor crecimiento Japón Aparato respiratorio patología Bronquio patología Enzima Inhibidor enzima Pulmón patología Protein-tyrosine kinase Transferases Tumor maligno Asia
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pulmonology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18691211
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/cncr.22593 
https://dx.doi.org/10.1002/cncr.22593
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