Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats
- Author
- CHOI, Goda1 2 3 4 5 ; HOFSTRA, Jorrit-Jan H1 2 5 ; ROELOFS, Joris J. T. H6 ; FLORQUIN, Sandrine6 ; BRESSER, Paul7 ; LEVI, Marcel2 ; VAN DER POLL, Tom2 3 4 ; SCHULTZ, Marcus J1 5
[1] Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[2] Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[3] Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[4] Center for Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[5] Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[6] Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[7] Department of Pulmonology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands - Source
Critical care medicine. 2007, Vol 35, Num 5, pp 1362-1368, 7 p ; ref : 43 ref
- CODEN
- CCMDC7
- ISSN
- 0090-3493
- Scientific domain
- Anesthesia, intensive care
- Publisher
- Lippincott, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- coagulation fibrinolysis inflammation mechanical ventilation pneumonia protein C
- Keyword (fr)
- Animal Fibrinolyse Homme Inflammation Pneumonie Protein C (activated) Protéine C Protéine recombinante Pseudomonas aeruginosa Rat Réanimation Soin intensif Ventilation mécanique Appareil respiratoire pathologie Bactérie Enzyme Hydrolases Mammalia Peptidases Poumon pathologie Pseudomonadaceae Pseudomonadales Rodentia Serine endopeptidases Vertebrata
- Keyword (en)
- Animal Fibrinolysis Human Inflammation Pneumonia Protein C (activated) Protein C Recombinant protein Pseudomonas aeruginosa Rat Resuscitation Intensive care Mechanical ventilation Respiratory disease Bacteria Enzyme Hydrolases Mammalia Peptidases Lung disease Pseudomonadaceae Pseudomonadales Rodentia Serine endopeptidases Vertebrata
- Keyword (es)
- Animal Fibrinólisis Hombre Inflamación Neumonía Protein C (activated) Proteína C Proteína recombinante Pseudomonas aeruginosa Rata Reanimación Cuidado intensivo Ventilación mecánica Aparato respiratorio patología Bacteria Enzima Hydrolases Mammalia Peptidases Pulmón patología Pseudomonadaceae Pseudomonadales Rodentia Serine endopeptidases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04I Blood coagulation. Blood cells / 002A04I01 General aspects, investigation methods, hemostasis, fibrinolysis
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02G Blood. Blood coagulation. Reticuloendothelial system
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B27 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy / 002B27B Intensive care medicine
- Discipline
- Anaesthesia. Reanimation. Transfusion. Cell therapy and gene therapy Molecular and cell biology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18701851
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1097/01.CCM.0000261888.32654.6D 
https://dx.doi.org/10.1097/01.CCM.0000261888.32654.6D
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