A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease
- Author
- COON, Keith D1 ; MYERS, Amanda J2 ; HALPERIN, Rebecca F1 ; MARLOWE, Lauren4 ; KALEEM, Mona4 ; WALKER, Douglas G3 ; RAVID, Rivka5 ; HEWARD, Christopher B6 ; ROGERS, Joseph3 ; PAPASSOTIROPOULOS, Andreas1 7 ; REIMAN, Eric M1 10 8 9 ; HARDY, John4 ; CRAIG, David W1 ; STEPHAN, Dietrich A1 10 ; WEBSTER, Jennifer A1 ; PEARSON, John V1 ; HU LINCE, Diane1 ; ZISMANN, Victoria L1 ; BEACH, Thomas G3 ; LEUNG, Doris4 ; BRYDEN, Leslie4
[1] Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Ariz, United States
[2] Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, Fla, United States
[3] Sun Health Research Institute, Sun City, Ariz, United States
[4] Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Md, United States
[5] Royal Dutch Academy of Sciences, Amsterdam, Netherlands
[6] Kronos Science Laboratories, Phoenix, Ariz, United States
[7] Division of Psychiatry Research, University of Zurich, Zurich, Switzerland
[8] Banner Alzheimer's Institute, Phoenix, United States
[9] Department of Psychiatry, University of Arizona, Tucson, United States
[10] Arizona Alzheimer's Consortium, Phoenix, Ariz, United States - Source
The Journal of clinical psychiatry. 2007, Vol 68, Num 4, pp 613-618, 6 p ; ref : 18 ref
- ISSN
- 0160-6689
- Scientific domain
- Psychology, psychopathology, psychiatry
- Publisher
- Physicians Postgraduate Press, Memphis, TN
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Age apparition Apolipoprotéine E Densité Démence Alzheimer Gène Sensibilité Tardif Déterminisme génétique Encéphale pathologie Génétique Maladie dégénérative Système nerveux central pathologie Système nerveux pathologie
- Keyword (en)
- Age of onset Apolipoprotein E Density Alzheimer disease Gene Sensitivity Late Genetic determinism Cerebral disorder Genetics Degenerative disease Central nervous system disease Nervous system diseases
- Keyword (es)
- Edad aparición Apolipoproteína E Densidad Demencia Alzheimer Gen Sensibilidad Tardío Determinismo genético Encéfalo patología Genética Enfermedad degenerativa Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C13 Organic mental disorders. Neuropsychology
- Discipline
- Neurology Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 18714992
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.4088/JCP.v68n0419 
https://dx.doi.org/10.4088/JCP.v68n0419
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