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Inhibitory and inductive effects of rifampin on the pharmacokinetics of bosentan in healthy subjects

Author
VAN GIERSBERGEN, P. L. M1 ; TREIBER, A2 ; SCHNEITER, R2 ; DIETRICH, H3 ; DINGEMANSE, J1
[1] Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, 4123 Allschwil, Switzerland
[2] Department of Preclinical Pharmacokinetics and Drug Metabolism, Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, 4123 Allschwil, Switzerland
[3] ClinPharmCologne, Cologne, Germany
Source

Clinical pharmacology and therapeutics. 2007, Vol 81, Num 3, pp 414-419, 6 p ; ref : 32 ref

CODEN
CLPTAT
ISSN
0009-9236
Scientific domain
Pharmacology drugs
Publisher
Nature Publishing, New York, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Antibactérien Antibiotique Antituberculeux Bosentan Effet inducteur Homme Individu sain Pharmacocinétique Rifampicine Rifamycine Antagoniste Inhibiteur synthèse protéique Récepteur endothéline Récepteur peptidergique
Keyword (en)
Antibacterial agent Antibiotic Antituberculous agent Bosentan Inductive effect Human Healthy subject Pharmacokinetics Rifampicin Rifamycin Antagonist Protein synthesis inhibitor Endothelin receptor Peptidergic receptor
Keyword (es)
Antibacteriano Antibiótico Antituberculoso Bosentan Efecto inductor Hombre Individuo sano Farmacocinética Rifampicina Rifamicina Antagonista Inhibidor síntesis proteica Receptor endotelina Receptor peptidérgico
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18715694

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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