Inhibitory and inductive effects of rifampin on the pharmacokinetics of bosentan in healthy subjects
- Author
- VAN GIERSBERGEN, P. L. M1 ; TREIBER, A2 ; SCHNEITER, R2 ; DIETRICH, H3 ; DINGEMANSE, J1
[1] Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, 4123 Allschwil, Switzerland
[2] Department of Preclinical Pharmacokinetics and Drug Metabolism, Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, 4123 Allschwil, Switzerland
[3] ClinPharmCologne, Cologne, Germany - Source
Clinical pharmacology and therapeutics. 2007, Vol 81, Num 3, pp 414-419, 6 p ; ref : 32 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antibactérien Antibiotique Antituberculeux Bosentan Effet inducteur Homme Individu sain Pharmacocinétique Rifampicine Rifamycine Antagoniste Inhibiteur synthèse protéique Récepteur endothéline Récepteur peptidergique
- Keyword (en)
- Antibacterial agent Antibiotic Antituberculous agent Bosentan Inductive effect Human Healthy subject Pharmacokinetics Rifampicin Rifamycin Antagonist Protein synthesis inhibitor Endothelin receptor Peptidergic receptor
- Keyword (es)
- Antibacteriano Antibiótico Antituberculoso Bosentan Efecto inductor Hombre Individuo sano Farmacocinética Rifampicina Rifamicina Antagonista Inhibidor síntesis proteica Receptor endotelina Receptor peptidérgico
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18715694
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.clpt.6100075 
https://dx.doi.org/10.1038/sj.clpt.6100075
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