Endothelial dysfunction and compromised eNOS/ Akt signaling in the thoracic aorta during the progression of Marfan syndrome
- Author
- CHUNG, A. W. Y1 ; AU YEUNG, K1 ; CORTES, S. F2 ; SANDOR, G. G. S3 ; JUDGE, D. P4 ; DIETZ, H. C4 ; VAN BREEMEN, C1
[1] Child and Family Research Institute and Departments of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
[2] Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil
[3] Division of Cardiology, Department of Pediatrics, British Columbia Children's Hospital, University of British Columbia, Vancouver, BC, Canada
[4] Howard Hughes Medical Institute and the Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States - Source
British journal of pharmacology. 2007, Vol 150, Num 8, pp 1075-1083, 9 p ; ref : 1 p.1/4
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Marfan syndrome; endothelium-dependent relaxation; nitric oxide; thoracic aorta; acetylcholine; Akt age-related disease progression
- Keyword (fr)
- Acétylcholine Age Akt protein kinase Aorte thoracique Azote monoxyde Endothélium Marfan syndrome Transduction signal Dysfonction endothéliale Appareil circulatoire Artère Maladie héréditaire Maladie système Neurotransmetteur Peau pathologie Tissu conjonctif pathologie Tissu élastique pathologie Vaisseau sanguin
- Keyword (en)
- Acetylcholine Age Akt protein kinase Thoracic aorta Nitric oxide Endothelium Marfan syndrome Signal transduction Endothelial dysfunction Circulatory system Artery Genetic disease Systemic disease Neurotransmitter Skin disease Connective tissue disease Elastic tissue disease Blood vessel
- Keyword (es)
- Acetilcolina Edad Akt protein kinase Aorta torácica Nitrógeno monóxido Endotelio Marfan síndrome Transducción señal Aparato circulatorio Arteria Enfermedad hereditaria Enfermedad sistémica Neurotransmisor Piel patología Tejido conjuntivo patología Tejido elástico patología Vaso sanguíneo
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B07 Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
- Discipline
- General pharmacology Sarcoidosis. Granulomatosis of undetermined origin. Connective tissue diseases. Vasculitides
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18716841
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjp.0707181 
https://dx.doi.org/10.1038/sj.bjp.0707181
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