Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines
- Author
- FURUKAWA, Y1 ; VU, H. A2 ; KANO, Y3 ; AKUTSU, M3 ; ODGEREL, T1 ; IZUMI, T3 ; TSUNODA, S3 ; MATSUO, Y4 ; KIRITO, K5 ; SATO, Y2 ; MANO, H6
[1] Department of Stem Cell Regulation, Center for Molecular Medicine, Jichi Medical School, Tochigi, Japan
[2] Division of Ultra fine Structure, Department of Clinical Pathology, Research Institute, International Medical Center of Japan, Tokyo, Japan
[3] Division of Hematology, Department of Internal Medicine, Tochigi Cancer Center, Tochigi, Japan
[4] Department of Cell Biology, Grandsoul Research Institute for Immunology, Nara, Japan
[5] Department of Hematology, University of Yamanashi, Yamanashi, Japan
[6] Department of Functional Genomics, Center for Molecular Medicine, Jichi Medical School, Tochigi, Japan - Source
Leukemia. 2007, Vol 21, Num 5, pp 1005-1014, 10 p ; ref : 39 ref
- CODEN
- LEUKED
- ISSN
- 0887-6924
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- FLT3 inhibitor FLT3 mutation cell-cycle arrest drug interaction
- Keyword (fr)
- Anticancéreux Cycle cellulaire Cytotoxicité Etude comparative Gène onc cellulaire Génétique Hématologie Inhibiteur Interaction médicamenteuse Lignée cellulaire établie Mutation Protooncogène Récepteur tyrosine kinase FLT3
- Keyword (en)
- Antineoplastic agent Cell cycle Cytotoxicity Comparative study C-Onc gene Genetics Hematology Inhibitor Drug interaction Established cell line Mutation Protooncogene Fms-like tyrosine kinase 3
- Keyword (es)
- Anticanceroso Ciclo celular Citotoxicidad Estudio comparativo Gen onc celular Genética Hematología Inhibidor Interacción medicamentosa Línea celular establecida Mutación Protooncogen
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18717287
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.leu.2404593 
https://dx.doi.org/10.1038/sj.leu.2404593
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