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Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 Expression

Author
RADZIEWICZ, Henry1 2 ; IBEGBU, Chris C1 ; ALTMAN, John D1 ; ROUSE, Barry T4 ; FREEMAN, Gordon J5 ; AHMED, Rafi1 ; GRAKOUI, Arash1 2 ; FERNANDEZ, Marina L1 ; WORKOWSKI, Kimberly A2 ; OBIDEEN, Kamil2 ; WEHBI, Mohammad2 ; HANSON, Holly L1 ; STEINBERG, James P2 ; MASOPUST, David1 ; WHERRY, E. John3
[1] Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, United States
[2] Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, United States
[3] Immunology Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, United States
[4] College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996, United States
[5] Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, United States
Source

Journal of virology. 2007, Vol 81, Num 6, pp 2545-2553, 9 p

ISSN
0022-538X
Scientific domain
Biochemistry, molecular biology, biophysics; Microbiology, infectious diseases; Virology
Publisher
American Society for Microbiology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Homme Hépatite virale C Lymphocyte Phénotype Virologie Appareil digestif pathologie Appareil digestif Foie pathologie Infection Virose
Keyword (en)
Human Viral hepatitis C Lymphocyte Phenotype Virology Digestive diseases Digestive system Hepatic disease Infection Viral disease
Keyword (es)
Hombre Hepatitis virica C Linfocito Fenotipo Virología Aparato digestivo patología Aparato digestivo Hígado patología Infección Virosis
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05C Virology / 002A05C10 Miscellaneous

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02G Viral hepatitis

Discipline
Infectious pathology Microbiology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18723447

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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