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Radical scavenging and cytochrome P450 3A4 inhibitory activity of bergaptol and geranylcoumarin from grapefruit

Author
GIRENNAVAR, Basavaraj1 ; JAYAPRAKASHA, G. K1 ; JADEGOUD, Y2 ; NAGANA GOWDA, G. A2 ; PATIV, Bhimanagouda S1
[1] Vegetable and Fruit Improvement Center, Department of Horticultural Sciences, 2119, Texas A&M University, College Station, TX 77843-2119, United States
[2] Center of Biomedical Magnetic Resonance, SGPGIMS, Lucknow 226 014, India
Source

Bioorganic & medicinal chemistry. 2007, Vol 15, Num 11, pp 3684-3691, 8 p

ISSN
0968-0896
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier Science, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Antioxidant activity CYP3A4 Coumarin Furocoumarin Grapefruit juice-drug interaction
Keyword (fr)
Activité biologique Antioxydant Coumarine dérivé Cytochrome P450 Drug-metabolizing enzyme Furocoumarine dérivé Huile essentielle Inhibiteur enzyme Interaction médicamenteuse Intercepteur radical Isolement Isozyme Jus fruit Lactone Origine végétale Pharmacognosie Pomélo Unspecific monooxygenase Bergaptol Cytochrome CYP3A4 Enzyme Oxidoreductases
Keyword (en)
Biological activity Antioxidant Coumarine derivatives Cytochrome P450 Drug-metabolizing enzyme Furocoumarine derivatives Essential oil Enzyme inhibitor Drug interaction Radical scavenger Isolation Isozyme Fruit juice Lactone Plant origin Pharmacognosy Grapefruit Unspecific monooxygenase Enzyme Oxidoreductases
Keyword (es)
Actividad biológica Antioxidante Citocromo P450 Drug-metabolizing enzyme Furocumarina derivado Aceite esencial Inhibidor enzima Interacción medicamentosa Interceptor radical Aislamiento Isozima Jugo fruta Lactona Origen vegetal Farmacognosia Toronja Unspecific monooxygenase Enzima Oxidoreductases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A04 Pharmacognosy. Homeopathy. Health food

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
18728517

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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