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Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells

Author
LUCCI, A1 ; HAN, T.-Y2 ; LIU, Y.-Y2 ; GLULIANO, A. E1 ; CABOT, M. C2
[1] Department of Surgical Oncology, John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California, United States
[2] John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California, United States
Source

Cancer. 1999, Vol 86, Num 2, pp 300-311 ; ref : 50 ref

CODEN
CANCAR
ISSN
0008-543X
Scientific domain
Medical oncology
Publisher
Wiley-Liss, New York, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Adénocarcinome Analogue Anthracyclines Antibiotique Anticancéreux Antihormone Antioestrogène Apoptose Association médicamenteuse Ciclosporine Composé non stéroïde Cytotoxicité Céramide Doxorubicine Glande mammaire Homme In vitro Interaction médicamenteuse Lignée cellulaire établie Mort cellulaire Mécanisme action Métabolisme Résistance multiple Résistance traitement Réversibilité Tamoxifène Lignée MCF7 PSC 833 Glande mammaire pathologie Tumeur maligne
Keyword (en)
Adenocarcinoma Analog Anthracyclins Antibiotic Antineoplastic agent Antihormone Antiestrogen Apoptosis Drug combination Ciclosporin Non steroid compound Cytotoxicity Ceramide Doxorubicin Mammary gland Human In vitro Drug interaction Established cell line Cell death Mechanism of action Metabolism Multiple resistance Negative therapeutic reaction Reversibility Tamoxifene Mammary gland diseases Malignant tumor
Keyword (es)
Adenocarcinoma Análogo Antraciclinas Antibiótico Anticanceroso Antihormona Antiestrógeno Apoptosis Asociación medicamentosa Ciclosporina Compuesto no esteroide Citotoxicidad Cerámida Doxorubicina Glándula mamaria Hombre In vitro Interacción medicamentosa Línea celular establecida Muerte celular Mecanismo acción Metabolismo Resistencia múltiple Resistencia al tratamiento terapeútico Reversibilidad Tamoxifeno Glándula mamaria patología Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1878653

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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