Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms
- Author
- CHEN, Chung-Yi1 ; LIU, Tsan-Zon2 ; CHEN, Ching-Hsein3 ; WU, Chih-Chung4 ; CHENG, Jiin-Tsuey5 ; YIIN, Shuenn-Jiun6 ; SHIH, Ming-Kuei7 ; WU, Mei-Jem5 ; CHERN, Chi-Liang8
[1] Basic Medical Science Education Center, Fooyin University, Ta-Liao, Kaohsiung Hsien, Taiwan, Province of China
[2] Center for Gerontological Research and Graduate Institute of Medical Biotechnology, Chang-Gang University, Kwei-Shan, Taoyuan, Taiwan, Province of China
[3] Graduate Institute of Biopharmaceutics, College of Life Sciences, National Chiayi University, Chiayi 600, Taiwan, Province of China
[4] Department of Nutrition and Health Science, Fooyin University, Ta-Liao, Kaohsiung Hsien 831, Taiwan, Province of China
[5] Department of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, Province of China
[6] Department of Nursing, Tajen University, Pintung, Taiwan, Province of China
[7] Department of Food and Beverage Management, National Kaohsiung Hospitality College, Kaohsiung, Taiwan, Province of China
[8] Department of Medical Technology, Fooyin University, Ta-Liao, Kaohsiung Hsien, Taiwan, Province of China - Source
Food and chemical toxicology. 2007, Vol 45, Num 7, pp 1268-1276, 9 p ; ref : 3/4 p
- CODEN
- FCTOD7
- ISSN
- 0278-6915
- Scientific domain
- Food science technology; Toxicology
- Publisher
- Elsevier Science, New York, NY
/
Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Bax Caspase 3 Isoobtusilactone A Mitochondrial transmembrane potential (AΨm) Reactive oxygen species
- Keyword (fr)
- Apoptose Carcinome hépatocellulaire Caspase Homme Mitochondrie Mort cellulaire Mécanisme action Production Stress oxydatif NAD(P)H oxidase Appareil digestif pathologie Enzyme Foie pathologie Hydrolases Peptidases Tumeur maligne
- Keyword (en)
- Apoptosis Hepatocellular carcinoma Caspase Human Mitochondria Cell death Mechanism of action Production Oxidative stress NAD(P)H oxidase Digestive diseases Enzyme Hepatic disease Hydrolases Peptidases Malignant tumor
- Keyword (es)
- Apoptosis Carcinoma hepatocelular Caspase Hombre Mitocondria Muerte celular Mecanismo acción Producción Estrés oxidativo Aparato digestivo patología Enzima Hígado patología Hydrolases Peptidases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 18829566
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.fct.2007.01.008 
https://dx.doi.org/10.1016/j.fct.2007.01.008
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